Hypothesis

Molecular docking analysis of curcumin analogues with COX-2

Sohilait et al. Bioinformation 13(11): 356- 359(2017) PDF, HTML-ABSTRACT

 
Hypothesis

Ymr210wp leads to the accumulation of phospholipids and steryl esters in yeast

Kumar et al. Bioinformation 13(11): 360-365 (2017) PDF, HTML-ABSTRACT

 
Hypothesis

In Silico Validation of D7 Salivary Protein-derived B- and T-cell Epitopes of Aedes aegypti as Potential Vaccine to Prevent Transmission of Flaviviruses and Togaviruses to Humans

Sankar et al. Bioinformation 13(11): 366-375 (2017) PDF, HTML-ABSTRACT

 
Hypothesis

Insights from the Molecular dynamics simulation of BcsD Subunit from K. xylinus

Kaur & Kulharia. Bioinformation 13(11): 376- 379(2017) PDF, HTML-ABSTRACT

 
Hypothesis

Insights from the protein-protein interaction network analysis of Mycobacterium tuberculosis toxin-antitoxin systems

Thakur et al. Bioinformation 13(11) 380-387 (2017) PDF, HTML-ABSTRACT

 
Hypothesis

Molecular docking based screening of a simulated HIF-1 protein model for potential inhibitors

Latha & Saddala. Bioinformation 13(11) 388-393 (2017) PDF, HTML-ABSTRACT

 
Hypothesis

Molecular modeling and simulation of three important components of Plant Pathogen Interaction cascade in Vigna mungo

Singh et al. Bioinformation 13(10): 323-326 (2017) PDF, HTML-ABSTRACT
 
Hypothesis

Robust Feature Selection Approach for Patient Classification using Gene Expression Data

Shahjaman et al. Bioinformation 13(10): 327-332 (2017)  PDF, HTML-ABSTRACT

 
Hypothesis

Host Infection beyond the Traditional Range of Sclerotium (Athelia) rolfsii with Physalis minima

Nandi et al. Bioinformation 13(10): 333-338 (2017)  PDF, HTML-ABSTRACT

 
Hypothesis

A QSAR model of Olanzapine derivatives as potential inhibitors for 5-HT2A Receptor

Mitra et al. Bioinformation 13(10): 339-342 (2017)  PDF, HTML-ABSTRACT

 
Hypothesis

Lubricin: A Principal Modulator of the Psychoneuroendocrine - Osteoimmune Interactome – Implications for Novel Treatments of Osteoarthritic Pathologies

Khakshooy et al. Bioinformation 13(10): 343-346 (2017)  PDF, HTML-ABSTRACT

 
Hypothesis

Cholera host response gene networks: preliminary studies

Shapshak et al. Bioinformation 13(10): 347- 351(2017)  PDF, HTML-ABSTRACT

 
Hypothesis

Clinical Immunology of Cholera – Current Trends and Directions for Future Advancement

Chiappelli et al. Bioinformation 13(10): 352- 355(2017)   PDF, HTML-ABSTRACT

 
Hypothesis

Molecular dynamics simulation analysis of Focal Adhesive Kinase (FAK) docked to solanesol as an anti-cancer agent

Daneial et al. Bioinformation 13(9): 274-283 (2017) PDF, HTML-ABSTRACT
 
Hypothesis

Molecular docking based screening of triterpenoids as potential G-quadruplex stabilizing ligands with anti-cancer activity

Sillapapongwarakorn et al. Bioinformation 13(9): 284-292 (2017)  PDF, HTML-ABSTRACT

 
Hypothesis

Molecular docking analysis of aplysin analogs targeting survivin protein

Shakeel et al. Bioinformation 13(9): 293-300 (2017) PDF, HTML-ABSTRACT

 
Hypothesis

Prediction aided In vitro analysis of octadecanoic acid from cyanobacterium Lyngbya sp. As a proapoptotic factor in eliciting anti-inflammatory properties

Manivannan et al. Bioinformation 13(9): 301-306 (2017) PDF, HTML-ABSTRACT

 
Hypothesis

Analysis of predicted B and T-cell epitopes in Der p 23, allergen from Dermatophagoides pteronyssinus

Fanuel et al. Bioinformation 13(9): 307-312 (2017) PDF, HTML-ABSTRACT

 
Hypothesis

Use of a neural network to predict normalized signal strengths from a DNA-sequencing microarray

Chilaka et al. Bioinformation 13(9): 313-317 (2017) PDF, HTML-ABSTRACT
 
Hypothesis

Insights from the analysis of alginate lyase protein model from Pseudomonas fluorescens towards the understanding of mucoid biofilm disruption

Singh & Kulkarni Bioinformation 13(9): 318-322 (2017) PDF, HTML-ABSTRACT

 
Hypothesis
Naturally occurring capsid protein variants L1 of human papillomavirus genotype 16 in Morocco
El-Aliani et al. Bioinformation 13(8): 241- 248 (2017) PDF, HTML-ABSTRACT
 
Hypothesis
Identification of long non-coding RNA in rice lines resistant to Rice blast pathogen Maganaporthe oryzae
Jain et al. Bioinformation 13(8): 249-255 (2017) PDF, HTML-ABSTRACT
 
Hypothesis
Marine sponge derived natural products as inhibitors of mycothiol-S-conjugate amidase
Saxena & Mishra. Bioinformation 13(8): 256- 260 (2017) PDF, HTML-ABSTRACT
 
Hypothesis
Druggability and Binding Site Interaction Studies of Potential Metabolites Isolated from Marine Sponge Aurora globostellata against Human Epidermal Growth Factor Receptor-2
Sugappriya et al. Bioinformation 13(8): 261- 268 (2017) PDF, HTML-ABSTRACT
 
Hypothesis
Potential Hemoglobin A/F role in clinical Malaria
Awasthi et al. Bioinformation 13(8): 269-273 (2017) PDF, HTML-ABSTRACT
 
Hypothesis
Designing Epitope Ensemble Vaccines against TB by Selection: Prioritising Antigens using Predicted Immunogenicity
J. Mistry & D.R. Flower, Bioinformation 13(7): 220-223  (2017) PDF, HTML-ABSTRACT
 
Hypothesis
A Genomic Signature for Genotyping Mycobacterium tuberculosis 
D. Tarazona et al. Bioinformation 13(7): 224-230 (2017) PDF, HTML-ABSTRACT
 

Hypothesis

Short peptide epitope design from hantaviruses causing HFRS
S. Sankar et al. Bioinformation 13(7): 231-236 (2017) PDF, HTML-ABSTRACT
 
Hypothesis
Docking Analysis of Verteporfin with YAP WW Domain
I. Kandoussi et al. Bioinformation 13(7): 237-241 (2017) PDF, HTML-ABSTRACT

 

Hypothesis
Protein-protein interfaces are vdW dominant with selective H-bonds and (or) electrostatics towards functional specificity
C. Nilofer et al. Bioinformation 13(6): 164-173 (2017) PDF, HTML-ABSTRACT

Hypothesis
Analysis of correlated mutations in Ras G-domain
E. Pathak, Bioinformation 13(6): 174-178 (2017) PDF, HTML-ABSTRACT

Hypothesis
Transcriptome wide identification and characterization of Starch Branching Enzyme in Finger Millet
R. Tyagi et al. Bioinformation 13(6): 179-184 (2017) PDF, HTML-ABSTRACT

Hypothesis
Structural insight into the binding mode of the C60-derivaitves against Helicobacter pylori Enoylpyruvate transferase
M. Teimouri et al. Bioinformation 13(6): 185-191 (2017) PDF, HTML-ABSTRACT

Hypothesis
Designing of a penta-peptide against drug resistant E. coli
S. Nagraa et al. Bioinformation 13(6): 192-195 (2017) PDF, HTML-ABSTRACT
 

Hypothesis
Combination of bone marrow mesenchymal stem cells and cartilage fragments contribute to enhanced repair of osteochondral defects
M. Abbas, Bioinformation 13(6): 196-201 (2017) PDF, HTML-ABSTRACT

Hypothesis
Serum and Plasma Metabolomic Biomarkers for Lung Cancer
N. Kumar et al. Bioinformation 13(6): 202-208 (2017) PDF, HTML-ABSTRACT

Hypothesis
Deciphering the Role of microRNAs in BRD4-NUT Fusion Gene Induced NUT Midline Carcinoma
E. Pathak et al. Bioinformation 13(6): 209-213 (2017) PDF, HTML-ABSTRACT

Hypothesis
Meta-Analysis Study to Evaluate the Association of MTHFR C677T Polymorphism with Risk of Ischemic Stroke
P.A. Abhinand, Bioinformation 13(6): 214-219 (2017) PDF, HTML-ABSTRACT

 
Hypothesis
Polymorphism of the PAI-1gene (4G/5G) may be linked with Polycystic Ovary Syndrome and associated pregnancy disorders in South Indian Women
M. Jesintha Mary et al. Bioinformation 13(5): 149-153 (2017) PDF, HTML-ABSTRACT
 
Hypothesis
QSAR based predictive modeling for anti-malarial molecules
DR Bharti & AM Lynn, Bioinformation 13(5): 154-159 (2017) PDF, HTML-ABSTRACT
 
Hypothesis
Linear epitope prediction in HPV type 16 E7 antigen and their docked interaction with human TMEM 50A structural model
U. Srivastava et al. Bioinformation 13(5): 122-130 (2017) PDF, HTML-ABSTRACT
 
Hypothesis
Molecular docking based screening of Listeriolysin-O for improved inhibitors
S. Ghafari, Bioinformation 13(5) 160-163 (2017) PDF, HTML-ABSTRACT
 
Hypothesis
Dengue Symptoms Significance in Anti-Dengue Drug Development: Road Less Travelled
A Paul & A Vibhuti, Bioinformation 13(5): 131-135 (2017) PDF, HTML-ABSTRACT
 
Hypothesis
Molecular docking analysis of nitisinone with homogentisate 1,2 dioxygenase
N Zolfaghari, Bioinformation 13(5): 136-139 (2017) PDF, HTML-ABSTRACT
 
Hypothesis
Competitive rational inhibitor design to 4-maleylaceto-acetate isomerase
N Zolfaghari, Bioinformation 13(5): 140-143 (2017) PDF, HTML-ABSTRACT
 
Hypothesis
Identification of inhibitors against α-Isopropylmalate Synthase of Mycobacterium tuberculosis using docking-MM/PBSA hybrid approach
P Pandey et al. Bioinformation 13(5): 144-148 (2017)  PDF, HTML-ABSTRACT
 
Hypothesis
Improved Annotations of 23 Differentially Expressed Hypothetical Proteins in Methicillin Resistant S. aureus
J Marklevitz & LK Harris, Bioinformation, 13(4) 104-110 (2017) PDF, HTML-ABSTRACT
 
Hypothesis
Influence of PCOS in Obese vs. Non-Obese women from Mesenchymal Progenitors Stem Cells and Other Endometrial Cells: An in silico biomarker discovery
A Desai et al. Bioinformation, 13(4) 111-115 (2017) PDF, HTML-ABSTRACT

Hypothesis
Molecular  Docking of Phytoligands to the viral protein receptor P. monodon  Rab7
J Joseph et al. Bioinformation, 13(4) 116-121 (2017) PDF, HTML-ABSTRACT

 

Hypothesis

Annotation of gene sequence and protein structure of brinjal EDS1

S. Sharma et al. Bioinformation 13(3) 54-63 (2017) PDF, HTML-ABSTRACT

 

Hypothesis

T-cell epitopes predicted from the Nucleocapsid protein of Sin Nombre virus restricted to 30 HLA alleles common to the North American population
S Sankar et al.
Bioinformation 13(3) 94-100 (2017) PDF, HTML-ABSTRACT

 

Hypothesis

Epitope design of L1 protein for vaccine production against Human Papilloma Virus types 16 and 18
S. Baidya et al.
Bioinformation 13(3) 86-93 (2017) PDF, HTML-ABSTRACT
 

Hypothesis
Antimicrobial activity of various ethanolic plant extracts against pathogenic multi drug resistant Candida spp.
S. Khan et al.
Bioinformation 13(3) 67-72 (2017) PDF, HTML-ABSTRACT

 

Software

optCluster: An R Package for Determining the Optimal Clustering

M. Sekula et al. Bioinformation 13(3) 101-103 (2017) PDF, HTML-ABSTRACT

 

Hypothesis
Identification and characterization of a cyclosporin binding cyclophillin from Staphylococcus aureus Newman

S Polley et al. Bioinformation 13(3) 78-85 (2017) PDF, HTML-ABSTRACT

 

Hypothesis

Analysis of EAWAG-BBD pathway prediction system for the identification of malathion degrading microbes

S. Sivakumar et al. Bioinformation 13(3) 73-77 (2017) PDF, HTML-ABSTRACT

 

Hypothesis

Quantitative Structure Activity Relationship study of anti-Hepatitis Peptides employing Random Forest and Extra Tree regressors
G. Mishra et al. Bioinformation 13(3) 60-62 (2017) PDF, HTML-ABSTRACT 

Hypothesis
A comparative molecular docking study of curcumin and methotrexate to dihydrofolate reductase
Y. Hobani et al. Bioinformation 13(3) 63-66 (2017) PDF, HTML-ABSTRACT

 

Hypothesis

Analysis of MAP kinase MPK4/MEKK1/MKK genes of Carica papaya L. comparative to other plant homologues
MH. Hamid et al. Bioinformation 13(2) 31-41 (2017) PDF, HTML-ABSTRACT
 

Hypothesis

Virtual screening following rational drug design based approach for introducing new anti amyloid beta aggregation agent
G. Rigi et al. Bioinformation 13(2) 42-45 (2017) PDF, HTML-ABSTRACT

 

Hypothesis
Nucleotide composition determines the role of translational efficiency in human genes
B. Halder et al. Bioinformation 13(2) 46-53 (2017) PDF, HTML-ABSTRACT
 

Hypothesis

Elucidation of the sequential transcriptional activity in Escherichia coli using time-series RNA-seq data

PS. Wong et al.  Bioinformation 13(1): 25-30 (2017) PDF, HTML-ABSTRACT

 

Hypothesis

Cloning and overexpression of non-coding RNA rprA in E.coli can increase the resistance to Kanamycin without osmotic shock

A. Sahni et al. Bioinformation 13(1): 21-24 (2017) PDF, HTML-ABSTRACT

 

Hypothesis
Substitutional Analysis of Orthologous Protein Families Using BLOCKS
PS. Sen Gupta et al. Bioinformation 13(1): 1-7 (2017) PDF, HTML-ABSTRACT

 

Hypothesis

High Throughput Virtual Screening to Identify Novel natural product Inhibitors for MethionyltRNA-Synthetase of Brucella melitensis

M. Kumari et al. Bioinformation 13(1): 8-16 (2017) PDF, HTML-ABSTRACT

 

Hypothesis

Computational study of ‘HUB’ microRNA in human cardiac diseases

R. Krishnan et al. Bioinformation 13(1): 17-20 (2017) PDF, HTML-ABSTRACT

 

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