Diaretinopathy database – A Gene database for diabetic retinopathy

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Title	Diaretinopathy database – A Gene database for diabetic retinopathy
Authors	Gopalakrishnan Vidhya¹* & Bhaskar Anusha²
Affiliation	¹Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur – 603 203, Tamil Nadu, India; ²Department of Biotechnology, CRD, PRIST University, Vallam, Thanjavur- 613403, Tamil Nadu, India
Email	vidhyavg@gmail.com; *Corresponding author
Article Type	Database
Date	Received December 12, 2013; Revised March 08, 2014; Accepted March 13, 2014; Published April 23, 2014
Abstract	Diabetic retinopathy, is a microvascular complication of diabetes mellitus and is a major cause of adult blindness. Despite advances in diagnosis and treatment the pathogenesis of diabetic retinopathy is not well understood. Results from epidemiological studies of diabetic patients suggest that there are familial predispositions to diabetes and to diabetic retinopathy. Therefore the main purpose of this database is to help both scientists and doctors in studying the candidate genes responsible for causing diabetic retinopathy. For each candidate gene official symbol, chromosome map, number of exons, GT-AG introns, motif, polymorphic variation and 3D structure are given respectively. In addition to molecular class and function of these genes, this database also provides links to download the corresponding nucleotide and amino acid sequences in FASTA format which may be further used for computational approaches. Therefore this database will increase the understanding of the genetics underlying the development or progression of diabetic retinopathy and will have an impact on future diagnostic, prevention and intervention strategies.
Availability	The database is freely available at http: diaretinopathydatabase.com
Keywords	Diabetic Retinopathy, Genes, SORD, ACE, VEGF, AGTR1
Citation	Vidhya & Anusha, Bioinformation 10(4): 235-240 (2014)
Edited by	P Kangueane
ISSN	0973-2063
Publisher	Biomedical Informatics
License	This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.