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Title

RDNAnalyzer: A tool for DNA secondary structure prediction and sequence analysis

 

Authors

Muhammad Afzal1, 2, Ahmad Ali Shahid1, Abida Shehzadi1*, Shahid Nadeem2 & Tayyab Husnain1

 

Affiliation

1Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan; 2Department of Bioinformatics and Biotechnology, GC University, Faisalabad, Pakistan.

 

Email

abida_ravian@hotmail.com; *Corresponding author

 

Article Type

Software

Date

Received June 26, 2012; Accepted July 05, 2012; Published July 21, 2012

 

Abstract

RDNAnalyzer is an innovative computer based tool designed for DNA secondary structure prediction and sequence analysis. It can randomly generate the DNA sequence or user can upload the sequences of their own interest in RAW format. It uses and extends the Nussinov dynamic programming algorithm and has various application for the sequence analysis. It predicts the DNA secondary structure and base pairings. It also provides the tools for routinely performed sequence analysis by the biological scientists such as DNA replication, reverse compliment generation, transcription, translation, sequence specific information as total number of nucleotide bases, ATGC base contents along with their respective percentages and sequence cleaner. RDNAnalyzer is a unique tool developed in Microsoft Visual Studio 2008 using Microsoft Visual C# and Windows Presentation Foundation and provides user friendly environment for sequence analysis. It is freely available.

 

Availability

http://www.cemb.edu.pk/sw.html

 

Keywords

Sequence analysis, DNA, nucleotides, Nussinov algorithm, C# language

 

Citation

Afzal et al. Bioinformation 8(14): 687-690 (2012)
 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.