Title

Comparative genomics - A perspective

Authors

Selvarajan Sivashankari¹ and Piramanayagam Shanmughavel^{2, *}

Affiliation

¹Department of Bioinformatics, Kongunadu Arts & Science College, Coimbatore - 641029; ^2,*Computational Biology Laboratory, Department of Bioinformatics, Bharathiar University, Coimbatore - 641046

Email

shanvel_99@yahoo.com;* Corresponding author

Article Type

Views & Challenges

Date

received November 17, 2006; revised January 26, 2007; accepted February 01, 2006; published online March 27, 2007

Abstract

The rapidly emerging field of comparative genomics has yielded dramatic results. Comparative genome analysis has become feasible with the availability of a number of completely sequenced genomes. Comparison of complete genomes between organisms allow for global views on genome evolution and the availability of many completely sequenced genomes increases the predictive power in deciphering the hidden information in genome design, function and evolution. Thus, comparison of human genes with genes from other genomes in a genomic landscape could help assign novel functions for un-annotated genes. Here, we discuss the recently used techniques for comparative genomics and their derived inferences in genome biology.

Keywords

comparative genomics; genome correspondence; gene identification, genome evolution

Citation

Edited by

P. Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.