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Title

Diaretinopathy database A Gene database for diabetic retinopathy

 

Authors

Gopalakrishnan Vidhya1* & Bhaskar Anusha2

 

Affiliation

1Department of Biotechnology, Faculty of Science and Humanities, SRM University, Kattankulathur 603 203, Tamil Nadu, India; 2Department of Biotechnology, CRD, PRIST University, Vallam, Thanjavur- 613403, Tamil Nadu, India

 

Email

vidhyavg@gmail.com; *Corresponding author

 

Article Type

Database

Date

Received December 12, 2013; Revised March 08, 2014; Accepted March 13, 2014; Published April 23, 2014

 

Abstract

Diabetic retinopathy, is a microvascular complication of diabetes mellitus and is a major cause of adult blindness. Despite advances in diagnosis and treatment the pathogenesis of diabetic retinopathy is not well understood. Results from epidemiological studies of diabetic patients suggest that there are familial predispositions to diabetes and to diabetic retinopathy. Therefore the main purpose of this database is to help both scientists and doctors in studying the candidate genes responsible for causing diabetic retinopathy. For each candidate gene official symbol, chromosome map, number of exons, GT-AG introns, motif, polymorphic variation and 3D structure are given respectively. In addition to molecular class and function of these genes, this database also provides links to download the corresponding nucleotide and amino acid sequences in FASTA format which may be further used for computational approaches. Therefore this database will increase the understanding of the genetics underlying the development or progression of diabetic retinopathy and will have an impact on future diagnostic, prevention and intervention strategies.

 

Availability

The database is freely available at http: diaretinopathydatabase.com

 

Keywords

Diabetic Retinopathy, Genes, SORD, ACE, VEGF, AGTR1

 

Citation

Vidhya & Anusha, Bioinformation 10(4): 235-240 (2014)
 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.