Title |
Identification of neuropeptides, flp-1 and flp-12 targeting neuromuscular system of rice root knot nematode (RRKN) Meloidogyne graminicola
|
Authors |
Uma Rao*, Prasoon Kumar Thakur, G Nagavara Prasad, Prakash Banakar & Mukesh Kumar
|
Affiliation |
Division of Nematology, Indian Agricultural Research Institute (IARI), New Delhi - 110012 |
|
umarao@iari.res.in; *Corresponding author |
Article Type |
Hypothesis |
Date |
Received December 11, 2012; Accepted December 21, 2012; Published February 21, 2013
|
Abstract |
Root-knot nematodes (RKNs), Meloidogyne spp, are found in all temperate and tropical areas, and are among the most damaging plant pathogens worldwide. M. graminincola is an economically important root parasite on upland, lowland and deepwater rice. FMRFamide-like peptides (FLPs) play significant role as neurotransmitters or neuromodulators in the nervous system and proposed as one of the important targets for the plant parasitic nematode management. Therefore, for the first time, we have cloned and characterized two neuropeptide genes (flp-1 and flp-12) from the cDNA of preparasitic second stage juveniles of M. graminicola. The flp-12 contains putative 22 residue long signal peptide at N-terminal suggesting function as an extra-cellular protein. We have found highly conserved motif LFRGR in flp-1. These two flp genes could be interesting and potential targets for functional validation to explore their utility for designing management strategies. |
Citation |
Rao et al.
Bioinformation 9(4): 182-186 (2013) |
Edited by |
P Kangueane
|
ISSN |
0973-2063
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Publisher |
|
License |
This is an Open Access article which permits unrestricted use,
distribution, and reproduction in any medium, provided the original
work is properly credited. This is distributed under the terms of
the
Creative Commons Attribution License. |