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Title

Identification of neuropeptides, flp-1 and flp-12 targeting neuromuscular system of rice root knot nematode (RRKN) Meloidogyne graminicola

 

Authors

Uma Rao*, Prasoon Kumar Thakur, G Nagavara Prasad, Prakash Banakar & Mukesh Kumar

 

Affiliation

Division of Nematology, Indian Agricultural Research Institute (IARI), New Delhi - 110012

 

Email

umarao@iari.res.in; *Corresponding author

 

Article Type

Hypothesis

 

Date

Received December 11, 2012; Accepted December 21, 2012; Published February 21, 2013

 

Abstract

Root-knot nematodes (RKNs), Meloidogyne spp, are found in all temperate and tropical areas, and are among the most damaging plant pathogens worldwide. M. graminincola is an economically important root parasite on upland, lowland and deepwater rice. FMRFamide-like peptides (FLPs) play significant role as neurotransmitters or neuromodulators in the nervous system and proposed as one of the important targets for the plant parasitic nematode management. Therefore, for the first time, we have cloned and characterized two neuropeptide genes (flp-1 and flp-12) from the cDNA of preparasitic second stage juveniles of M. graminicola. The flp-12 contains putative 22 residue long signal peptide at N-terminal suggesting function as an extra-cellular protein. We have found highly conserved motif LFRGR in flp-1. These two flp genes could be interesting and potential targets for functional validation to explore their utility for designing management strategies.  

 

Citation

Rao et al  Bioinformation 9(4): 182-186 (2013)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.