Title |
SALMONELLABASE - An online database of druggable targets of Salmonella species
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Authors |
Ophilia Benedict Pushpa & Muthaiyan Xavier Suresh* |
Affiliation |
Department of Bioinformatics, Sathyabama University, Jeppiaar Nagar, Rajiv Gandhi Salai, Chennai - 600 119
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|
xaviersuresh@gmail.com; *Corresponding author
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Article Type |
Database |
Date |
Received July 18, 2012; Accepted July 30, 2012; Published August 03, 2012
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Abstract |
Salmonellosis is one of the most common and widely distributed food borne diseases caused by Salmonella serovars. The emergence of multi drug resistant strains has become a threatening public health problem and targeting unique effectors of this pathogen can be considered as a powerful strategy for drug design. SalmonellaBase is an online web portal serving as an integrated source of information about Salmonella serovars with the data required for the structural and functional studies and the analysis of druggable targets in Salmonella. We have identified several target proteins, which helps in the pathogenicity of the organism and predicted their structures. The database will have the information on completely sequenced genomes of Salmonella species with the complete set of protein sequences of the respective strains, determined structures, predicted protein structures and biochemical pathways of the respective strains. In addition, we have provided information about name and source of the protein, Uniprot and Protein Data Bank codes and literature information. Furthermore, SalmonellaBase is linked to related databases and other resources. We have set up a web interface with different search and display options so that users have the ability to get the data in several ways. SalmonellaBase is a freely available database.
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Availability |
http://www.salmonellabase.com/
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Keywords |
SalmonellaBase, Database, Drug Design, Salmonella, Druggable Targets
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Citation |
Pushpa & Suresh,
Bioinformation 8(15): 734-737 (2012) |
Edited by |
P Kangueane
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ISSN |
0973-2063
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Publisher |
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License |
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License. |