Title

Authors

Affiliation

¹Department of Bioinformatics, School of Biotechnology and Health Sciences, Karunya University, Karunya Nagar, Coimbatore – 641114, Tamil Nadu, India; ²Department of Biotechnology, Periyar Maniammai University, Thanjavur – 613403, Tamil Nadu, India.

Email

ersekaran@gmail.com; *Corresponding author

Article Type

Hypothesis

Date

Received July 09, 2012; Accepted July 16, 2012; Published August 03, 2012

The role of hydrophobic force in biological function through the formation of several local macro-molecular structures is evident. Carbon is the element that contributes to biological function in living systems. We show that carbon distribution is related to protein activity using an example. The carbon distribution profile is foreseen to help undestand unfolded and misfolded regions of protein structures. The carbon distribution profile in a toxin protein that is found associated with the toxic shock syndrome is described in this study. The carbon profile provides insight to the association of specific residues responsible for toxicity.

Keywords

carbon distribution, mutational study, hydrophobic interation, toxic protein, mitogenicity, carbon profile

Citation

Akila et al. Bioinformation 8(15): 720-721 (2012)
 

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.