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Title |
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Toward multimodality oral cancer diagnosis in the XXI century: Blending cutting edge imaging and genomic/proteomic definition of suspicious lesions |
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Authors |
Anh D Le1*, Diana V Messadi2, Joel B Epstein3, Petra Wilder-Smith4 |
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Affiliation |
1Center for Craniofacial Molecular Biology, University of Southern California, School of Dentistry, Los Angeles, CA 90033; 2Section of Oral Medicine, Division of Oral Biology & Medicine, UCLA School of Dentistry, University of California, Los Angeles, CA 90095; 3College of Dentistry and Cancer Center, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612; 4Beckman Laser Institute, University of California, Irvine 1002 Health Sciences Rd East, Irvine, CA 92612 |
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Article Type |
Current Trends
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Date |
Received September 17, 2010; Accepted October 9, 2010; Published January 06, 2011 |
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Abstract |
If emergent genomic and proteomic approaches to early oral cancer detection are to be successful, a means of reliably and comprehensively identifying high-risk tissue sampling sites constitutes an essential step in the oral cancer screening process. Recent studies have determined that in vivo Optical Coherence Tomography (OCT) is a quick and user-friendly tool for detecting and mapping oral lesions, and that it can enhance diagnostic accuracy when using high resolution diagnostic techniques such as in vivo microscopy. Therefore OCT can potentially provide a means of improving the clinical usefulness of novel diagnostic approaches such as proteomics by identifying sites that need to be sampled |
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Citation |
Le et al. Bioinformation 5(7): 304-306 (2011) |
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Edited by |
Francesco chiappelli
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ISSN |
0973-2063
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Publisher |
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License |
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License. |