Title

Transforming scientific evidence into better consumer choices 

Authors

Janet G Bauer^1* & Francesco Chiappelli¹

Affiliation

¹Division of Restorative Dentistry, June and Paul Ehrlich Endowed Program in Geriatric Dentistry, 23-008E CHS, UCLA School of Dentistry, PO Box 951668, 10833 Le Conte Avenue, Los Angeles, California 90095-1668 

Email

jbauer@dent.ucla.edu

310-825-57747

310-641-0523

Article Type

Prediction model

Date

Received December 15, 2010; Accepted December 21, 2010; Published January 06, 2011
 

Translational research using evidence-based and comparative effectiveness research continues to evolve, becoming a useful tool in improving informed consent and decision-making in the clinical setting. While in development, emerging technologies, including cellular and molecular biology, are leading to establishing evidence-based dental practices. One emerging technology, which conjoins bench proteomic findings to clinical decision-making for treatment intervention, is the Translational Evidence Mechanism. This mechanism was developed to be a foundation for a compact between researcher, translational researcher, clinician, and patient. The output of such a mechanism is the clinical practice guideline (CPG), an interactive tool for dentists and patients to game evidence in reaching optimum clinical decisions that correspond to individual patient preferences and values. As such, the clinical practice guideline requires the vesting of decision, utility, and cost best evidence. Evidence-based research provides decision data, a first attempt at supporting decision-making by providing best outcome data. Since then comparative effectiveness research has emerged, using systematic review analysis to compare similar treatments or procedures in maximizing the choice of the most effective cost/benefit option within the context of best evidence. With innovation in the clinical practice guideline for optimizing efficacy and comparative effectiveness research, evidence-based practices will shape a new approach to health-based systems that adhere to shared decision-making between bench scientists, healthcare providers and patients.  

Keywords

Translational evidence, clinical decision-making, clinical practice guidelines (CPGs), evidence-based practice, comparative efficacy and effectiveness research 

Citation

Bauer & Chiappelli, Bioinformation 5(7): 297-299 (2011)

Edited by

Francesco chiappelli

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.