Title

The microarray manual curation tool (MMCT): A Webserver for microarray probe evaluations

Authors

Dan Tulpan^1,*; Luc Belliveau Serge Léger¹

Affiliation

¹Institute of Information Technology National Research Council of Canada Moncton, New Brunswick, E1A 7R1, Canada

Email

dan.tulpan@nrc-cnrc.gc.ca

Article Type

Web Server

Date

Received January 7 2010, Accepted February 8 2010, Published February 28 2010

Abstract

Quality control of probe sequences is a major concern in microarray technology. The presence of poor quality probes has a negative impact on the microarray data analysis process. The Microarray Manual Curation Tool (MMCT) is a web server application that provides computational and visual means to investigate the quality of individual probes for oligo microarrays. The MMCT quality metrics assess the free energy of hybridization and the secondary structure of duplexes formed by selected targets and probes, which are specific to various microarray platforms.

Keywords

Bioinformatics, web server, microarrays, visualization.

Availability

http://www.nrcbioinformatics.ca/mmct

Citation

Tulpan & Leger, Bioinformation 4(8): 344-346 (2010)

Edited by

P. Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.