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Title
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Specific gene hypomethylation and cancer: New insights into coding region feature trends
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Authors
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Elias Daura-Oller, Maria Cabre, Miguel A. Montero, Jose L. Paternain, Antoni Romeu
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Affiliation
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Biochemistry and Biotechnology Department, Faculty of Chemistry, Rovira i Virgili, University (URV), c/ Marcel·li Domingo, s/n. Campus Sescelades, 43007 Tarragona, Spain
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Phone |
34977558188
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Fax |
34977558232
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Article Type
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Hypothesis
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Date
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received December 02, 2008; accepted January 12, 2009; published April 21, 2009
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Abstract
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Giving coding region structural features a role in the hypomethylation of specific genes, the occurrence of G+C content, CpG islands, repeat and retrotransposable elements in demethylated genes related to cancer has been evaluated. A comparative analysis among different cancer types has also been performed. In this work, the inter-cancer coding region features comparative analysis carried out, show insights into what structural trends/patterns are present in the studied cancers.
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Keywords |
epigenetics; cancer; CpG islands; hypomethylation
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Citation |
Daura-Oller et al. Bioinformation 3(8): 340-343 (2009)
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Edited by |
P. Kangueane
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ISSN |
0973-2063
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Publisher |
Biomedical Informatics | |
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License
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This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License. |