Title

Prognostic value of modified shock index in sepsis

Authors

Sanchit Uppal^1,*, Mini Bhatnagar¹, Abhinav Meelu¹, Johnly Jacob¹ & Ena Sharma²

Affiliation

¹Department of General Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, Haryana-133203, India; ²Department of Periodontics, Rayat Bahra Dental College and Hospital, Mohali, Punjab-140301, India; *Corresponding author

Email

Sanchit Uppal - E - mail: sanchit@mmumullana.org

Mini Bhatnagar - E - mail: minibhatnagar@mmumullana.org

Abhinav Meelu - E - mail: abhinav.meelu@mmumullana.org

Johnly Jacob - E - mail: drjohnlyj@gmail.com

Ena Sharma - E - mail: dr.sharma_ena@yahoo.co.in

Article Type

Research Article

Date

Received April 1, 2025; Revised April 30, 2025; Accepted April 30, 2025, Published April 30, 2025

Abstract

Sepsis is a life-threatening condition requiring early diagnosis and severity assessment in the emergency department (ED) to guide timely interventions. Therefore, it is of interest to evaluate the Modified Shock Index (MSI) as a prognostic tool for sepsis and compared its sensitivity and specificity to the quick sequential organ failure assessment (qSOFA) score in 150 sepsis patients, based on Sepsis-3 guidelines. Clinical data, including MSI and qSOFA scores, were collected at admission and patient outcomes were analyzed for mortality and hospital stay duration. An MSI cut-off of 1.28 predicted mortality with high accuracy (AUC 0.946, sensitivity 91.76%, specificity 90.77%), outperforming the qSOFA score (AUC 0.840). MSI is a reliable, easy-to-use bedside tool that surpasses the quick sequential organ failure assessment score in predicting sepsis prognosis, aiding in early identification and management of high-risk patients.

Keywords

Triage, emergency department, quick sequential organ failure assessment (qSOFA), modified shock index (MSI), sepsis

Citation

Uppal et al. Bioinformation 21(4): 614-617 (2025)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.