Title
Intravenous dexmedetomidine versus levobupivacaine for hemodynamic response towards skull pin insertion
Authors
Aishwarya Srinivasan*, Shraddha Naik & PB Jamale
Affiliation
Department of Anesthesiology, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth (Deemed To Be University), Karad, Maharashtra, India; *Corresponding author
Aishwarya Srinivasan - E - mail: aishu01.as@gmail.com
Shraddha Naik - E - mail: drshraddhag09@gmail.com
P B Jamale - E - mail: jamalepb@gmail.com
Article Type
Research Article
Date
Received March 1, 2025; Revised March 31, 2025; Accepted March 31, 2025, Published March 31, 2025
Abstract
Local anesthetics such as levobupivacaine, along with fentanyl and intravenous dexmedetomidine, have shown potential in reducing sympathetic activation and tension. Therefore, it is of interest to compare intravenous dexmedetomidine with levobupivacaine. Patients were randomly assigned to two groups of 40 each, designated as Group D and Group S, with measures including baseline, heart rate, mean arterial pressure, systolic blood pressure, and diastolic blood pressure. At baseline, no significant difference in saturation was seen across the Groups (p = 0.10). Likewise, during induction and at subsequent intervals (1 minute before and after skull pin placement, as well as at 3, 5 and 10 minutes thereafter), Spo2 levels were similar across the two groups (all p > 0.05). We concluded that the scalp block using fentanyl-levobupivacaine and intravenous dexmedetomidine has comparable efficacy in diminishing the hemodynamic response associated with the skull pin head.
Keywords
Hemodynamic response, skull pin head, intravenous dexmedetomidine, levobupivacaine, local anesthesia, fentanyl
Citation
Srinivasan et al. Bioinformation 21(3): 434-440 (2025)
Edited by
Neelam Goyal & Shruti Dabi
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
