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Title

Risk of cardiovascular events among celiac disease patients: A meta-analysis review

 

Authors

Saad Shams1,#, Vanessa Vidaurre Corrales2,#, Ibrahim Marouf Yasin Al Shyyab3, Akshat Banga4, Ameer Mustafa Farrukh5, Moza Ali Alzaabi3, Majd Atef Albeetar3, Sem Josue Nsanh Yao6, Kavya Remala7, Mohamad Emad Aldeen Mahfouz3, Navneeth Jayaprakash8 & Sawai Singh Rathore9,*

 

Affiliation

1Department of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, USA; 2Department of Internal Medicine, Universidad Privada del Valle, Cochabamba, Bolivia; 3Department of Internal Medicine, University of Sharjah, Sharjah, UAE; 4Department of Internal Medicine, Mt. Auburn Hospital, Cambridge, USA; 5Department of Internal Medicine, University of Galway School of Medicine, Galway, Ireland; 6Department of Internal Medicine, Western Reserve Hospital, Cuyahoga Falls, USA; 7Department of Internal Medicine, Konaseema Institute of Medical Sciences, Amalapuram, India; 8Department of Internal Medicine, D.Y. Patil Medical College, Kolhapur, India; 9Department of Internal Medicine, Dr. Sampurnanand Medical College, Jodhpur, Rajasthan, India; *Corresponding author; #Equal contribution

 

Email

Saad Shams - E - mail: saadshams1@icloud.com

Vanessa Vidaurre Corrales - E - mail: vanessavidaurre23@hotmail.com

Ibrahim Marouf Yasin Al Shyyab - E - mail: ibrahimshayyab6000@yahoo.com

Akshat Banga - E - mail: bangaakshat1996@gmail.com

Ameer Mustafa Farrukh - E - mail: Amf62888@gmail.com

Moza Ali Alzaabi - E - mail: Alzaabi.maj@gmail.com

Majd Atef Albeetar - E - mail: Albitarmajd@gmail.com

Sem Josue Nsanh Yao - E - mail: semyao.cchmc@gmail.com

Kavya Remala - E - mail: kavyas.remala@gmail.com

Mohamad Emad Aldeen Mahfouz - E - mail: Mohd.mahfouzz@gmail.com

Navneeth Jayaprakash - E - mail: dr.navneethjp@gmail.com

Sawai Singh Rathore - E - mail: sawais.rathore77@gmail.com

 

Article Type

Review

 

Date

Received March 1, 2025; Revised March 31, 2025; Accepted March 31, 2025, Published March 31, 2025

 

Abstract

A review on the association between celiac disease and cardiovascular events using multiple databases and random effects models is of interest. The overall prevalence of cardiovascular events in celiac patients was 9.3%. However, there was no significant increase in overall cardiovascular risk or myocardial infarction compared to the general population. Known data shows that celiac disease was linked to a higher risk of atrial fibrillation, stroke, congestive heart failure and cardiomyopathy. Thus, there is a need to monitor cardiovascular health in celiac patients to mitigate potential risks.

 

Keywords

Celiac disease; cardiovascular events; myocardial infarction; atrial fibrillation; stroke

 

Citation

Shams et al. Bioinformation 21(3): 375-382 (2025)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.