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Title

ABO blood group antigens in saliva - A cross sectional study

 

Authors

S. Surekha*, K Saraswathi Gopal, B.G. Harsha vardhan & T. Swathi

 

Affiliation

Department of Oral medicine and radiology, Meenakshi Ammal Dental College and Hospital, Chennai, Tamilnadu, India; *Corresponding author

 

Email

S. Surekha - E - mail: mailtosurekha21@gmail.com; Phone: +91 7904026402
K Saraswathi Gopal - E - mail: drsaraswathik@gmail.com; Phone: +91 9443291115
B.G. Harsha vardhan - E - mail: bgharshavardhan@yahoo.com; Phone: +91 9840042337
T. Swathi - E - mail: swathi.march91@gmail.com; Phone: +91 9962484011

 

Article Type

Research Article

 

Date

Received March 1, 2025; Revised March 31, 2025; Accepted March 31, 2025, Published March 31, 2025

 

Abstract

Blood group antigens are present on red blood cells and in bodily fluids like saliva, making them useful in forensic investigations when blood or tissue samples are unavailable. Therefore, it is of interest to determine the secretory status of A, B, H antigens in saliva to correlate it with blood samples. A prospective, randomized, cross-sectional study of 102 individuals was conducted, with saliva collected using drooling and gauze methods. Blood group was determined using slide agglutination. A strong correlation (Pearson coefficient r = .980**) was observed between ABH antigens in saliva and blood group as well as with dry salivary sample (p = 0.04*). Thus, the feasibility and reliability of identifying ABO blood group antigens in saliva, supporting its potential as a non-invasive alternative for forensic and clinical applications is shown.

 

Keywords

ABO blood groups, secretors, saliva, ABH blood group antigens, agglutination

 

Citation

Surekha et al. Bioinformation 21(3): 329-333 (2025)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.