Title
Pathological predictors for curettage and cementation outcome in proximal tibial giant cell tumors
Authors
Deepak Kumar1, Ashish Kumar1, Nilam Bhasker2,*, Sanjeev Kumar1, Atin Singhai3, Priyank Pratap1, Ankit Sriwastava1 & Madhusudan Mishra1
Affiliation
1Department of Orthopaedic Surgery, King George’s Medical University, Lucknow, Uttar Pradesh-226003, India; 2ESIC Hospital, ESIC Hospital Complex, Sarojini Nagar, Lucknow, Uttar Pradesh-226023, India; 3Department of Pathology, King George’s Medical University, Lucknow, Uttar Pradesh-226003, India; *Corresponding author
Deepak Kumar - E - mail: drdeepakkumarkgmc@gmail.com
Ashish Kumar - E - mail: drashish_kumar20202@yahoo.com
Nilam Bhasker - E - mail: nilam2711@gmail.com
Sanjeev Kumar - E - mail: sanjeevkumar98@gmail.com
Atin Shanghai - E - mail: atinsinghai@yahoo.com
Priyank Pratap - E - mail: priyanksingh441@gmail.com
Ankit Sriwastava - E - mail: ankitshiv130294@gmail.com
Madhusudan Mishra - E - mail: msm.kgmc@gmail.com
Article Type
Research Article
Date
Received February 1, 2025; Revised February 28, 2025; Accepted February 28, 2025, Published February 28, 2025
Abstract
Proximal tibia giant cell tumors (GCT) are aggressive with high-recurrence rate, function-affecting and benign neoplasms. Therefore, it is of interest to report the pathological predictors for curettage and cementation outcome in proximal tibial giant cell tumors. Hence, 32 patients treated with curettage, poly-methyl-methacrylate (PMMA) cementation and locking plate fixation between 2018 and 2022 was included in this study. The average age of patients was 28.1 ± 6.9 years and most tumors were Grade 2 (campanacci grade) with 62.5% cortical involvement. The average musculo-skeletal tumor society (MSTS) score was 27.2 ± 4.2 with acceptable function. Thus, tumor grade and cortical involvement were the main predictors of recurrence, reflecting the need for targeted treatment.
Keywords
Giant cell tumor (GCT), tumor grading, recurrence risk, cortical bone involvement pathological predictors, functional outcomes
Citation
Kumar et al. Bioinformation 21(2): 190-195 (2025)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
