Title

Osseo-integration potential of zirconia versus titanium implants

Authors

Pratesh Dholabhai¹, Surabhi Thakur², Deepak Sharma^3,*, Narendra Sathish⁴, Sunil kar⁵ & Sameer Gupta⁶

Affiliation

¹Department of Oral and Maxillofacial Surgery, K.M Shah Dental College and Hospital, Sumandeep Vidyapeeth Deemed to be University, Pipariya, Vadodara, Gujarat, India; ²Department of Prosthodontics and Crown & Bridge, Seema dental college and hospital, Rishikesh, Uttarakhand, India; ³Oral And Maxillofacial Surgeon, Private Practioner, JP Dental Clinic, Morena, Madhya Pradesh- 476001, India; ⁴Department of Prosthodontics and Implantology, CAPF’s Composite Hospital BSF Guwahati Assam, India; ⁵Department of prosthodontics, IDS, SOA University, Bhubaneswar, Odisha, India; ⁶Department of Oral & Maxillofacial Surgery, Inderprastha Dental College and Hospital, Sahibabad, Ghaziabad, Uttar Pradesh - 201010, India; *Corresponding author

Email

Pratesh Dholabhai - E - mail: pratesh1994@gmail.com; Phone: 9429075992
Surabhi Thakur - E - mail: thakursurabhi8@gmail.com;
Deepak Sharma - E - mail: drdeepaksharma2900@gmail.com
Narendra Sathish - E - mail: narendra.sathish@gmail.com
Sunil kar - E - mail: sunilkar888@gmail.com
Sameer Gupta - E - mail: sameer.gupta83@yahoo.in; Phone: 9873941402

Article Type

Research Article

Date

Received February 1, 2025; Revised February 28, 2025; Accepted February 28, 2025, Published February 28, 2025

Abstract

The success of dental implants depends on osseo-integration because titanium (Ti) maintains good mechanical stability while zirconia (Zr) prevents bacterial adhesion. The early-stage adhesion of MG-63 osteo-blast-like cells to Ti surfaces reached 78% ± 2.5% during the initial period (p<0.05). However, Zr demonstrated superior long-term cell proliferation and mineralization throughout the analysis period (p<0.05). The alkaline phosphatase (ALP) levels at day 7 remained comparable between Ti (1.25 ± 0.09 U/mL) and Zr (1.18 ± 0.07 U/mL) while Zr showed better growth of mineralized surface at day 14. Nonetheless, additional testing using animal subjects are required to confirm Zr as a suitable substitute for Ti implants.

Keywords

Zirconia implants, titanium implants, osseo-integration, osteoblasts, in vitro study, dental implants

Citation

Dholabhai et al. Bioinformation 21(2): 161-164 (2025)

Edited by

Hiroj Bagde MDS, (PhD), PGDCR, PGDHHM, PGDL, PGDM

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.