Title
Fluoride enigma in end stage renal disease
Authors
Paramaturi Sharon Rose, Kurpad Nagaraj Shashidhar*, Uppalamethi Munilakshmi & Muthyala Meghanath
Affiliation
Department of Biochemistry, Sri Devaraj Urs Medical College, Kolar, Tamaka, Karnataka, India; *Corresponding author
Paramaturi Sharon Rose - E - mail: sharonhoney06@sduaher.ac.in
Kurpad Nagaraj Shashidhar - E - mail: drshashikn1971@sduaher.ac.in
Uppalamethi Munilakshmi - E - mail: munilakshmiu@sduaher.ac.in
Muthyala Meghanath - E - mail: megha.sdumc.frrl@gmail.com
Article Type
Research Article
Date
Received September 1, 2024; Revised September 30, 2024; Accepted September 30, 2024, Published September 30, 2024
Abstract
Fluoride is an essential micro-mineral. Chronic exposure to fluoride affects collagen biosynthesis, insulin resistance, diabetes mellitus and kidney damage. Present prospective study, include 142 subjects categorised into group I and II. Serum samples was separated and stored appropriately. Statistical significant values were observed in urea, creatinine, calcium, magnesium, fluoride and IL6 in DN. Serum fluoride, total proteins, and calcium showed a positive correlation in group I versus group II. Fluoride is one of the key adjunct and surrogate molecule in causation of micro-vascular complications of diabetes.
Keywords
Fluoride, IL-6, diabetic nephropathy
Citation
Sharon Rose et al. Bioinformation 20(9): 998-1001 (2024)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
