Title

Effect of obesity and hypertension on left ventricular geometry and function among asymptomatic Indian adults

Authors

Shree C Mamatha^{1, *}, KS Prashanth² & B. Girija²

Affiliation

¹Department of Physiology, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research, Kolar, Karnataka, India; ²Department of Physiology, Bangalore Medical College & Research Institute, Bengaluru, Karnataka, India; *Corresponding author

Email

Mamatha Shree C -E-mail: 15mamathashree@gmail.com; mamathashreec@sduaher.ac.in

Prashanth KS -E-mail: kspdoc@gmail.com

Girija B -E-mail: girija_kumar_40@yahoo.co.in

Article Type

Research Article

Date

Received August 1, 2024; Revised August 31, 2024; Accepted August 31, 2024, Published August 31, 2024

Hypertension & obesity are important independent predictors of cardiovascular morbidity & mortality specifically left ventricular (LV) functions. With the Objectives to examine the effect of obesity & hypertension on echocardiographic parameters of geometry, systolic, and diastolic functions of left ventricle in asymptomatic adults the cross-sectional study was conducted with 100 individuals (60 male & 40 female). Their Blood Pressure & Body Mass Index was recorded following which they were divided into obese normotensives & non-obese hypertensive. Echocardiographic parameters indicating LV geometry and function were recorded. Data was statistically analysed with Unpaired t test considering p value <0.05 as significant. LV geometry and LV systolic function parameters were significantly altered in non-obese hypertensive. Parameters of LV diastolic functions were affected in obese normotensives. 54% of obese normotensives had LV diastolic dysfunction & 58% of non-obese hypertensive had LV diastolic dysfunction. 2% of obese non-hypertensive individuals had LV systolic dysfunction & 6% of non-obese hypertensive had LV diastolic dysfunction. Hypertension significantly affects LV geometry, LV systolic and diastolic function. Obesity affects LV geometry & diastolic functions of LV even in individuals with preserved systolic function.

Keywords

Left ventricular diastolic function, left ventricular geometry, left ventricular systolic function, non-obese hypertensive, obese normotensives

Citation

Mamatha et al. Bioinformation 20(8): 862-867 (2024)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.