Title
Anti-oxidant, anti-inflammatory and antimicrobial activity of aqueous extract from acerola and amla
Authors
Chellathurai Burnice Nalina Kumari1,*, Namasivayam Ambalavanan1, Shanmugam Rajesh Kumar2, Jaideep Mahendra1 & Uma Sudhakar3
Affiliation
1Department of Periodontics, Meenakshi Ammal Dental College and Hospital, Meenakshi Academy of Higher Education and Research, Chennai, Tamil Nadu, India; 2Nano biomedicine Lab, Centre for Global Health Research, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India; 3Department of Periodontics, Thai Moogambigai Dental College and Hospital, Tamil Nadu, India; *Corresponding author
C. Burnice Nalina Kumari - E-mail: drburnice.perio@madch.edu.in; Phone: +91 9790944335
N. Ambalavanan - E-mail: drambal@gmail.com; Phone: +91 9841052868
S. Rajesh Kumar - E-mail: rajeshkumars.sdc@saveetha.com; Phone: +91 9629739263
Jaideep Mahendra - E-mail: drjaideep.perio@madch.edu.in; Phone: +91 9444963973
Uma Sudhakar - E-mail: uma.perio@drmgrdu.ac.in; Phone: +91 9962075729
Article Type
Research Article
Date
Received July 1, 2024; Revised July 31, 2024; Accepted July 31, 2024, Published July 31, 2024
Abstract
Amla, scientifically known as emblica officinalis and Acerola (malphigian emarginata) both are Vitamin C fruits possess varied medicinal properties being used for preventive disease health management strategies. Therefore, it is of interest to explore the antioxidant, anti-inflammatory, antibacterial, and cytotoxic properties of aqueous extracts from Acerola and Amla. Hence, the anti-inflammatory activity of Acerola and amla was assessed using the bovine serum albumin denaturation assay (BSA Assay), antioxidant properties were compared using DPPH (2,2-diphenyl-1-picrylhydrazyl) assay. Both extracts antibacterial activities were evaluated through the agar well diffusion technique against oral pathogens and Brine shrimp lethality assay for cytotoxicity. The current research sheds light on natural remedies for oxidative stress-related diseases, inflammatory conditions and bacterial infections, offering promising avenues for disease management and preventive healthcare strategies especially in the treatment of oral health diseases like periodontitis.
Keywords
Amla extract, Acerola extract, Antioxidant agent, Anti-inflammatory agent, Antibacterial agent, Biocompatibility.
Citation
Nalina Kumari et al. Bioinformation 20(7): 765-770 (2024)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
