Title
Analysis of salivary alpha-L-fucosidase and salic acid among oral sub-mucous fibrosis patients
Authors
Sayan Mitra1, Satish Gujjarlapudi2, Nishath Sayed Abdul3, Pallavi Singh4, Debanti Giri5, Ekta Pansheriya6 & Ramanpal Singh Makkad7,*
Affiliation
1Department of Oral Medicine and Radiology, RKDF Dental College, Bhopal, M.P., India; 2DMD,MBS,BDS, Associate Dentist, Familia dental, 804 S Green River road, Evansville, IN 47715; 3Faculty of Oral Pathology, Department of OMFS and Diagnostic Sciences, College of Medicine and Dentistry, Riyadh Elm University, Riyadh, Kingdom of Saudi Arabia; 4Reader & Head, Department of Public Health Dentistry, Saraswati Dental College &Hospital, Lucknow, U.P. 5Associate Professor, Department of Oral Medicine and Radiology, Dr R Ahmed Dental College and Hospital ,West Bengal, India; 6Department of Pedodontics and Preventive Dentistry, Faculty of Dental Science, Dharmsinh Desai University, Nadiad. 7Department of Oral Medicine and Radiology, New Horizon Dental College and Research Institute, Bilaspur, Chhattisgarh, India; *Corresponding author
Sayan Mitra - E-mail: dr.sayanbds@gmail.com
Satish Gujjarlapudi - E-mail: satishgujjarlapudi@gmail.com
Nishath Sayed Abdul - E-mail: nishathsayed@riyadh.edu.sa
Pallavi Singh - E-mail: pallavirolisingh@gmail.com
Debanti Giri - E-mail: drdebantigiri@gmail.com
Ekta Pansheriya - E-mail: dr.ekta151@gmail.com
Ramanpal Singh Makkad - E-mail: drramanpal@gmail.com
Article Type
Research Article
Date
Received June 1, 2024; Revised June 30, 2024; Accepted June 30, 2024, Published June 30, 2024
Abstract
The salivary concentrations of alpha L fucosidase (AFU) and salic acid (SA) in oral submucous fibrosis patients and compare it with healthy controls is of interest to dentists. 40 patients of OSMF and 40 healthy controls were included. Estimation of AFU and SA in saliva and serum was carried out in every patient. The serum level of AFU was 37.4±26.8 in OSMF patients and saliva level of AFU was 35.4±14.5. The serum level of AFU was 19.2±4.3 in control group and saliva level of AFU was 35.4±14.5 in control group. The serum level of SA was 20.32±2.71 in OSMF patients and saliva level of SA was 18.21±2.40. The serum level of SA was 4.89 ±1.17 in control group and saliva level of SA was 3.13 ±1.04 in control group. Estimation of concentration of SA and AFU in saliva can be effective biomarker in diagnosis of OSMF.
Keywords
alpha L fucosidase, salic acid, saliva.
Citation
Mitra et al. Bioinformation 20(6): 669-673 (2024)
Edited by
Dr. Vini Mehta MDS
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
