Title |
Serum iron, zinc and copper among Indian patients with leukoplakia, oral submucous fibrosis and oral squamous cell carcinoma
|
Authors |
Pratibha Kavle1, Rashi Dubey2, Annaluru Sri Sasank Tejaswee3, Gunmeek Kaur4, Animesh Mondal5, Vishal D Patel6, Keyur Jitendrakumar Patel7 & Ansee Rameshbhai Vaghani8
|
Affiliation |
1Department of Oral Pathology, Bharati Vidyapeeth (Deemed to be University) dental college and hospital, Navi Mumbai, India; 2Department of Pedodontics and Preventive Dentistry, SharadPawar Dental College and Hospital(DattaMegheInstitute of Higher Education and Research (Deemed to be a University), Sawangi, Wardha, Maharashtra, India; 3Department of Oral and Maxillofacial Surgery, Kalinga Institute of Dental Science, KIIT Deemed to Be University, Bhubaneswar, Odisha, India; 4Department of Oral and Maxillofacial Surgery, LuxmiBai Dental College and Hospital, Patiala. 5Deptartment of Oral and Maxillofacial Pathology, Dr.R.Ahmed Dental College & Hospital, Kolkata. 6Department of Orthodontics and Dentofacial Orthopaedic, Dhramsinh Desai University, Nadiad, Gujarat, India. 7Government Medical College Surat, Gujarat, India; 8Department of Oral Pathology and Microbiology, Manubhai Patel Dental College, Vadodara, India; *Corresponding author
|
|
Pratibha Kavle - E-mail: pratibhakavle@gmail.com Rashi Dubey - E-mail: rashidubey0186@gmail.com Annaluru Sri SasankTejaswee - E-mail: sasankannaluru@gmail.com Gunmeek Kaur - E-mail: gunmeekkaur@gmail.com Animesh Mondal - E-mail: animeshmondal106@gmail.com Vishal D Patel- E-mail: drvishalortho@gmail.com Keyur Jitendrakumar Patel - E-mail: drkeyurpatel22sep@gmail.com Ansee Rameshbhai Vaghani - E-mail: Avagh708@gmail.com |
Article Type |
Research Article
|
Date |
Received June 1, 2024; Revised June 30, 2024; Accepted June 30, 2024, Published June 30, 2024
|
Abstract |
The serum levels of iron, zinc and copper in patients with leukoplakia, oral submucous fibrosis (OSMF) and oral squamous cell carcinoma (OSCC) and compare them with normal subjects is of interest to dentists. The effort was to determine a parameter that will aid the initial diagnosis, a more efficient therapy plan, and ultimately a better prognosis. Participants in the study comprised 40 healthy normal volunteers, 60 patients diagnosed with leukoplakia, 60 patients diagnosed with OSCC, and 60 patients diagnosed with OSMF. After fasting for the whole night, blood samples were taken from each participant. There was analysis by inductively coupled plasma-optical emission spectrometry (ICP-OES) for the determination of trace elements; iron, copper, and zinc. The serum levels of iron and zinc in normal subjects was greater as compared to patients with leukoplakia, OSMF and OSCC. There was increase in serum copper levels in patients with oral leukoplakia, OSMF and OSCC as compared with normal subjects.
|
Keywords |
OSMF, Leukoplakia, OSCC, serum, iron, zinc, copper.
|
Citation |
Kavle et al. Bioinformation 20(6): 660-664 (2024)
|
Edited by |
Dr. Vini Mehta MDS
|
ISSN |
0973-2063
|
Publisher |
|
License |
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
|
|