Title
Epidemiology, molecular prevalence and prevention on canine parvovirus in India: A review
Authors
Vanjavaka Pavana Jyothi1, Mohana Subramanian Bhaskaran2,* & Vijay A.K.B. Gundi1,*
Affiliation
1MBIG Research Laboratory, Department of Biotechnology, Vikrama Simhapuri University, Nellore - 524 324, Andhra Pradesh, India; 2Cisgen Biotech Discoveries, IITM Research Park, Chennai-600113, Tamilnadu, India; *Corresponding author
Vanjavaka Pavana Jyothi - E-mail:pavani.bit@gmail.com
Mohana Subramanian Bhaskaran - E-mail: bhaskaran.mohana@gmail.com
Vijay A.K.B. Gundi - E-mail: gundi.vijay@gmail.com
Article Type
Review
Date
Received May 1, 2024; Revised May 31, 2024; Accepted May 31, 2024, Published May 31, 2024
Abstract
Canine parvovirus (CPV) is a highly contagious and lethal virus that causes severe gastroenteritis and myocarditis in young dogs. In 1978, CPV has rapidly spread worldwide, resulting in outbreaks and high morbidity rates among dog populations. Over a decade, CPV has undergone genetic changes, leading to the emergence of different genotypes (CPV-2a, CPV-2b, and CPV-2c), which have expanded its host range to include cats and tissue culture cells. This review focuses on CPV-2 outbreaks in India from 2010 to 2023, analyzing gene lengths covering 274-438 amino acids in the VP2 gene which are collected from the NCBI database to investigate CPV epidemiology and diversity. The study highlighted substantial differences in seroprevalence over the period for CPV-2 (7%), CPV-2a (45%), CPV-2b (12%), and CPV-2c (36%). Our study found significant seroprevalence differences among CPV variants, with CPV-2a being the most prevalent, underscoring the need for effective diagnostic and preventive strategies.
Keywords
Canine parvovirus, Haemorrhagic enteritis, vaccination, immunisation failures, maternal antibodies, CPV variants
Citation
Jyothi et al. Bioinformation 20(5): 536-546 (2024)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
