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Title

Evaluation of CoVid-19 infection among vaccinated and unvaccinated individuals using biochemical markers

 

Authors

Allavarapu Ramya Sree1,*, K. Sethumadhavan1, S.P. Tejaswi Pullakanam 2 & Purimitla Usharani3

 

Affiliation

1Department of Microbiology, Aarupadai Veedu Medical College and Hospital, Vinayaka Mission's Research Foundation (VMRF-DU), Puducherry, Tamil Nadu, India; 2Department of Biochemistry, Gayatri Vidya Parishad Institute of Health Care and Medical Technology, Marikavalasa, Visakhapatnam, Andhra Pradesh, India; 3Department of Microbiology, Dr. Patnam Mahender Reddy Institute of Medical Sciences, Chevella, Ranga Reddy District, Telangana, India; *Corresponding author

 

Email

Allavarapu Ramya Sree - E-mail: ramyams619@@gmail.com; Phone: +91 9491726905

K Sethumadhavan - E-mail: sethumadhavanmicro@gmail.com; Phone: 0413-2611246

S.P. Tejaswi Pullakanam - E-mail: tejaswibio22@gmail.com; Phone: +91 8985081842

Purimitla Usharani - E-mail: purimitlausha2@gmail.com; Phone: +91 6304297389

 

Article Type

Research Article

 

Date

Received March 1, 2024; Revised March 31, 2024; Accepted March 31, 2024, Published March 31, 2024

 

Abstract

The evaluation of infection rate for CoVid-19 cases among vaccinated and unvaccinated individuals using haematological parameters is of interest. Data such as age, gender, occupation, location, signs and symptoms, length of symptoms, date of sample collection and report generation, status of vaccinations, and outcome available in the database was used in this analysis. Ferritin levels, D-dimer values, CRP, troponin-1 levels and platelet count of each CoVid-19 patient were recorded and analysed. Data shows that maximum number of cases was reported during the second wave 143 (51.07%). The common age group affected was 31-40 years 28.56%. The common symptom identified was weakness in arms and legs among the unvaccinated group of CoVid-19 positive group. However, common symptom identified was fatigue (87%) among those who received only the first dose of CoVid vaccine. Nonetheless, the symptom identified was hair loss (68%) among those who received both the doses of CoVid vaccine. Thus, data shows that people do experience severe and life-threatening COVID-19 infection despite receiving the vaccination. Nonetheless, the infection is mild and very few individuals require hospitalization. No deaths are reported in the group that received the vaccination. This is in contrast to the unvaccinated group, which had a severe CoVid-19 infection with few deaths reported.

 

Keywords

CoVid-19, vaccinated, unvaccinated, symptoms, prevalence, ferritin, D-dimer, CRP

 

Citation

Ramya Sree et al. Bioinformation 20(3): 223-228 (2024)

 

Edited by

Peter N Pushparaj

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.