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Title

Advanced CT angiography in detecting rare arterio-venous malformations: Addressing diagnostic challenges in obscure gastrointestinal bleeding

 

Authors

Swathi Tapaswi Kanna1, Kaushik Rajavel2, Shoa Nayyer3, Pritika Gnanasekaran4, Priyadarshini Ramesh5 & Anshuman Kumar Panda6,*

 

Affiliation

1Department of Medicine, Royal Albert Edward Infirmary, Wigan Wrightington and Leigh Teaching Hospitals NHS Foundation Trust, Wigan, United Kingdom; 2Department of Orthopaedics, Madras Medical College, Chennai, Tamil Nadu, India; 3Department of Surgery, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal Karnataka, India; 4Department of Medicine, Global Medical Centre, Salem, Tamil Nadu, India; 5Department of Obstetrics & Gynaecology, Madras Medical College, Chennai, Tamil Nadu, India; 6Department of Critical Care (ICU), Asian Institute of Medical Sciences, Faridabad, Haryana, India; *Corresponding author

 

Email

Swathi Tapaswi Kanna - E - mail: thapaswikanna111@gmail.com; Phone no: +44 7405763119

Kaushik Rajavel - E - mail: kaushikr246@gmail.com; Phone no: +91 9677391827

Shoa Nayyer - E - mail: shoanayyer9@gmail.com; Phone no: +91 8587970110

Pritika Gnanasekaran - E - mail: prithika33378@gmail.com; Phone no: +91 9500631112

Priyadarshini Ramesh - E - mail: priyaramesh1198@gmail.com; Phone no: +91 8825735755

Anshuman Kumar Panda - E - mail: shreeami1998@gmail.com; Phone no: +91 9971132935

 

Article Type

Research Article

 

Date

Received December 1, 2024; Revised December 31, 2024; Accepted December 31, 2024, Published December 31, 2024

 

Abstract

Gastrointestinal bleeding is a common clinical issue, but obscure gastrointestinal bleeding (OGIB) presents significant diagnostic challenges, especially when caused by arteriovenous malformations (AVMs). This study explored the role of advanced CT angiography (CTA) in diagnosing and managing AVM-related OGIB in 100 patients. CTA identified AVMs in 12% of cases where standard endoscopy failed (p < 0.001) and guided successful surgical control of bleeding in 95% of these cases. The sensitivity of CTA (92%) was significantly higher compared to other imaging modalities (68%; p = 0.002), particularly for small or inaccessible lesions. These findings underscore CTA's crucial role in improving diagnostic accuracy and enabling targeted therapeutic interventions for challenging cases of OGIB.

 

Keywords

Obscure gastrointestinal bleed, arteriovenous malformation, CT angiography, vascular anomalies, surgical management.

 

Citation

Kanna et al. Bioinformation 20(12): 1917-1921 (2024)

 

Edited by

A Prashanth

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.