Title
Impact of the COVID-19 pandemic on care delivery, follow-up, and outcomes in chronic myeloid leukemia patients: An observational cohort study
Authors
Pramod Kumar Pamu1,*, Tara Roshni Paul1, Naval Chandra2, Sadashivudu Gundeti3 & K Radhika1
Affiliation
1Department of Pathology, Nizam's Institute of Medical Sciences (NIMS), Punjagutta, Hyderabad 500082, Telangana, India; 2Department of Medicine, Nizam's Institute of Medical Sciences( NIMS), Punjagutta, Hyderabad 500082, Telangana, India; 3Department of Medical Oncology, Department of Pathology, Nizam's Institute of Medical Sciences (NIMS), Punjagutta, Hyderabad 500082, Telangana, India; *Corresponding author
Pramod Kumar Pamu - E - mail: pramodkumarpamu@gmail.com
Tara Roshni Paul - E - mail: troshnip@yahoo.co. in
Naval Chandra - E - mail: naval31@yahoo.co.in
Sadashivudu Gundeti - E - mail: drssgundeti@yahoo.com
Radhika K - E - mail: radhika_setti@yahoo.com
Article Type
Research Article
Date
Received December 1, 2024; Revised December 31, 2024; Accepted December 31, 2024, Published December 31, 2024
Abstract
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm that comprises a chronic phase. Therefore, it is of interest to evaluate the impact of care delivery and loss of follow-up or defaulted treatment due to the COVID-19 pandemic affecting the outcome in known chronic myeloid leukemia patients. Data was retrospectively retrieved and prospectively evaluated from the known and treated CML patients. A questionnaire was prepared for history. Bone marrow slides stained with Giemsa stain and multi-color flow cytometry were used for the evaluation of blast type in all blast crisis cases. A total of 961 new CML cases were reported, age range from 21 to 78 years, results were analyzed in three different cohort groups based on their time of diagnosis. Loss of follow-up was noticed mainly during the COVID-19 period and thereafter because of non-compliance. Data shows that about 53% of cases showed no hematological response and about 34% transformed into a CML blast crisis phase.
Keywords
Covid 19, chronic myeloid leukemia, care delivery
Citation
Pamu et al. Bioinformation 20(12): 1813-1818 (2024)
Edited by
Vini Mehta
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
