Title
Evaluation of oral cavity squamous cell carcinoma undergoing selective neck dissection with positive nodes among Indian patients
Authors
Salini Kumari Dash1, Asutosh Pradhan1, Madhurima Rudra2, Ravi Kumar3,*, Sushil Kumar Sahoo1 & Manisha Mohanty4
Affiliation
1Department of Oral and Maxillofacial Surgery, Hi-Tech Dental College and Hospital, Bhubaneswar, Odisha, India; 2Department of Allied Health science, Sister Nivedita University, Kolkata, West Bengal, India; 3Department of Dentistry, Heritage Institute of Medical Sciences, Varanasi, Uttar Pradesh-221005, India; 4Private Consultant, Bhubaneswar, Odisha, India; *Corresponding author
Salini Kumari Dash - E - mail: salinikumaridash@gmail.com
Asutosh Pradhan - E - mail: asupupulutosh@gmail.com
Madhurima Rudra - E - mail: Drrims16madhu@gmail.com
Ravi Kumar - E - mail: drravi1102@gmail.com
Sushil Kumar Sahoo - E - mail: doc_sksahoo@yahoo.com
Manisha Mohanty - E - mail: Manishamohanty2808@gmail.com
Article Type
Research Article
Date
Received December 1, 2024; Revised December 31, 2024; Accepted December 31, 2024, Published December 31, 2024
Abstract
Selective neck dissection (SND) is commonly performed in patients with node-positive oral cavity squamous cell carcinoma (OCSCC) to manage regional metastasis while minimizing morbidity. Therefore, it is of interest to evaluate the effectiveness of SND in patients with node-positive OCSCC. We conducted a retrospective cohort study including 150 patients diagnosed with node-positive OCSCC who underwent selective neck dissection. Patient demographics, tumor characteristics, surgical outcomes and adjuvant therapies were recorded. The primary endpoints were disease-free survival (DFS) and overall survival (OS). Secondary endpoints included regional recurrence and postoperative complications. Selective neck dissection is a viable surgical option for patients with node-positive OCSCC, providing acceptable regional control and survival outcomes. Extra capsular spread and positive surgical margins are significant prognostic factors for recurrence. Careful patient selection and meticulous surgical technique are essential for optimizing outcomes.
Keywords
Oral cavity squamous cell carcinoma, selective neck dissection, node-positive, disease-free survival, overall survival, regional recurrence.
Citation
Dash et al. Bioinformation 20(12): 1800-1803 (2024)
Edited by
Vini Mehta
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
