Title

Salivary diagnostics: Bridging dentistry and medicine: A systematic review

Authors

Deepa Benni¹, KM. Pallavi², Tejaswi Maddukuri³, Richa Singh⁴, Jayant Kumar Gahlot^5,*, Parama Basu⁶ & Anukriti Kumari⁷

Affiliation

¹Department of Dentistry, Karnataka Medical College and Research Institute, Hubballi, India; ²Department of Dentistry, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India; ³Department of Dentistry, Lenora institute of dental science, NTR University, Rajanagaram, Rajamahendravaram, Andhra Pradesh, India; ⁴Department of Oral and Maxillofacial Surgery, Shree Bankey Bihari Dental College & Research Centre, Ghaziabad, India; ⁵Department of Oral Medicine and Radiology, Santosh Dental College, Ghaziabad, Uttar Pradesh, India; ⁶Department of Periodontics, House Surgeon, Dr. R Ahmed Dental College and Hospital, Kolkata, West Bengal, India; ⁷Department of Oral Medicine and Radiology, School of Dental Sciences, Sharda University, Greater Noida, India; *Corresponding author

Email

Deepa Benni - E - mail: deepbenni@gmail.com
KM. Pallavi - E - mail: drkmpallavi1999@gmail.com
Tejaswi Maddukuri - E - mail: maddukuri.tejaswi123@gmail.com
Richa Singh - E - mail: richashishodia@hotmail.com
Jayant Kumar Gahlot - E - mail: drjayantgahlot28@gmail.com
Parama Basu - E - mail: paramabasu24@gmail.com
Anukriti Kumari - E - mail: anukritishrma0@gmail.com

Article Type

Review

Date

Received December 1, 2024; Revised December 31, 2024; Accepted December 31, 2024, Published December 31, 2024

Abstract

Saliva has emerged as a non-invasive, easily accessible biofluid for diagnostic purposes in dentistry and medicine. Biomarkers in saliva, such as proteins, enzymes, nucleic acids, and metabolites, reflect both systemic and oral health. Advances in molecular science, nanotechnology, and bioinformatics have enabled highly accurate assays for early disease detection, monitoring, and treatment guidance. Salivary diagnostics are promising for identifying conditions like diabetes, HIV, COVID-19, autoimmune disorders, cardiovascular diseases, and oral diseases such as periodontal disease and oral cancer. To fully realize its potential, regulatory approval, standardized procedures, and further research on salivary biomarkers are essential.

Keywords

Biomarkers, diagnostic, saliva.

Citation

Benni et al. Bioinformation 20(12): 1754-1759 (2024)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.