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Title

Effect of hypochlorous acid in open wound healing

 

Authors

Spurgeon raj Jalem1 & Purimitla Usharani2,*

 

Affiliation

1Department of Emergency medicine and critical care, Bliss Hospital, Murad Nagar Road, Mehidipatnam, Hyderabad - 500028, Telangana, India; 2Department of Microbiology, Dr. Patnam Mahender Reddy Institute of Medical Sciences, Chevella, Ranga Reddy, Telangana, India; *Corresponding author

 

Email

Spurgeon Raj Jalem - E - mail: jyothipgis@gmail.com; blisshospital1@gmail.com

Purimitla Usharani - E - mail: purimitlausha2@gmail.com

 

Article Type

Research Article

 

Date

Received November 1, 2024; Revised November 30, 2024; Accepted November 30, 2024, Published November 30, 2024

 

Abstract

Wound healing is a complex process involving multiple stages to restore the integrity and function of damaged tissues. Researchers are exploring the therapeutic potential of HOCl in treating infections and inflammatory conditions, given its efficacy in killing pathogens and modulating immune responses. The present study is a prospective study aimed to know the wound healing nature of HOCl on open wounds in patients attending out-patient department. The study was conducted for a period of one year Jan 2023 to Jan 2024 at Bliss Hospital, Hyderabad, Telangana district, India. Hypochlorous acid (Vida solutions, Pvt.Ltd) was used to irrigate the open wound. Among the 10 reported cases, three were females and seven were males. Most of the cases were reported from middle age and old-age persons except one paediatric case of age 3 years a female girl. A male patient of age 72 years with co-morbidities diabetes and hypertension suffering with chronic wound on left leg for a period of 35 years because of thorn prick injury. The complete wound healing took nearly 15 weeks in this patient. The wound healing takes place 8 to 15 weeks maximum in all the 10 cases and the above findings concluded that, these features lead to a stabilized HOCl solution as an ideal wound care agent.

 

Keywords

Hypochlorous acid, chronic wound, infection, co-morbidities

 

Citation

Jalem & Usharani, Bioinformation 20(11): 1619-1622 (2024)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.