Title

Therapeutic use of oral gastrografin in treating acute adhesive small bowel obstruction

Authors

Sameer Soni¹, Surya Prakash², Saurabh Rai¹ & Sanish Philips^1,*

Affiliation

¹Department of Surgery, Chirayu Medical College & Hospital, Bhopal, India; ²General Surgery Unit, New Korba Superspeciality Hospital, Chhattisgarh, India; *Corresponding author

Email

Sameer Soni - E - mail: sameersoni13187@gmail.com

Surya Prakash - E - mail: dr.surya170@gmail.com

Saurabh Rai - E - mail: saurabhav21@gmail.com

Sanish Philips - E - mail: sanish4507@gmail.com

Article Type

Research Article

Date

Received October 1, 2024; Revised November 5, 2024; Accepted November 5, 2024, Published November 5, 2024

Abstract

Adhesions are a major cause of small bowel obstruction, posing significant challenges in diagnosis, treatment and prevention. Adhesive small bowel obstruction has a substantial impact on morbidity and imposes a considerable socioeconomic burden. Therefore, it is of interest to study the therapeutic use of oral gastrografin in treating acute adhesive small bowel obstruction. Acute small bowel obstruction (SBO), accounting for 6-30% of cases. Adhesions are responsible for approximately 65-75% of SBO cases, necessitating careful assessment and management. This study, conducted at Chirayu Medical College & Hospital, Bhopal, India from June 2021 to May 2022, included 87 patients with 94 episodes of adhesive SBO. Initial conservative treatment resolved 63 episodes (67.02%) within 48 hours. The remaining 31 episodes (32.98%) were subjected to a Gastrografin challenge, where 23 cases (74.2%) showed successful dye transit to the colon within 24 hours, while 8 cases (25.8%) required surgical intervention. The findings suggest the Oral Gastrografin represents a significant advancement in the conservative management of acute adhesive small bowel obstruction, offering a non-invasive, effective and safe alternative to surgery for many patients. Its integration into clinical practice can enhance patient care and improve clinical outcomes in the management of ASBO.

Keywords

Adhesive small bowel obstruction (ASBO), conservative management of ASBO, gastrografin challenge, postoperative adhesions, non-operative treatment of intestinal obstruction.

Citation

Soni et al. Bioinformation 20(11): 1447-1452 (2024)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.