Title
Rejuvenation of bone volume with CGF and i-PRF in intra-osseous defects
Authors
Koppu Sitamahalakshmi1,*, Sai Krishna Bingi2, Govardhani Krishna Kumar3, Yanamala Bhuvanesh4, Surapaneni Keerthi Sai5 & Subramanyam Parkavi6
Affiliation
1Department of Periodontology & Implantology, Kamineni Institute of Dental Sciences, Narketpally, Nalgonda, India; 2Department of Conservative Dentistry & Endodontics Kamineni Institute of Dental Sciences, Narketpally, Nalgonda, India; 3Department of Periodontology & Implantology, Government dental college and hospital, Vijayawada, AP, India; 4Department of Periodontology & Implantology, Government dental college and hospital, Vijayawada, AP, India; 5Department of Oral Maxillo-facial Pathology, Kamineni Institute of Dental Sciences, Narketpally Nalgonda, India; 6Department of Periodontology & Implantology, Government dental college and hospital, Vijayawada, AP, India; *Corresponding author
K Sitamahalakshmi - E-mail: drcita18k@gmail.com; Phone: +91 7995267134
Sai Krishna Bingi - E-mail: saikrrishnagoud@gmail.com
Govardhani Krishna Kumar - E-mail: govardhanikrishnakumar@gmail.com
Y Bhuvanesh - E-mail: ybhuvan7@gmail.com
S Keerthi - keethu.surapaneni@gmail.com
S Parkavi - E-mail: parkavi2212@gmail.com
Article Type
Research Article
Date
Received January 1, 2024; Revised January 31, 2024; Accepted January 31, 2024, Published January 31, 2024
Abstract
The risk of further periodontal breakdown increases with a deep intrabony defect. Non-surgical periodontal therapy could pose a challenge and surgical intervention is mainly required to manage the defect. Autologous platelet concentrates such as Injectable platelet rich fibrin (i-PRF) and concentrated growth factor (CGF) may improve surgical outcome due to its enrichment with growth factors. Total of 04 patients involved in this study. After conventional flap debridement of intrabony defects, CGF is placed in 2 patients and the other 2 patients received i-PRF in their respective intrabony defects. Volumetric analysis was done pre-operative and 6 months post operatively in both the groups. Bone volume is significantly increased in both CGF and i-PRF group but higher in CGF group when compared to i-PRF group has high regenerative and reconstructive growth factors which helps aids in early and high bone fill when compared to i-PRF.
Keywords
Concentrated growth factor (CGF), injectable platelet rich fibrin (i-PRF), regeneration, bone volume, platelet concentrates generation
Citation
Sitamahalakhsmi et al. Bioinformation 20(1): 85-90 (2024)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
