Title
Deterioration of lung function and its association with eosinophil count
Authors
Bama Rajanayagam1, 2, Sundaramahalingam Manikandan*3, & Nag Anand4
Affiliation
1Bharath Institute of Higher Education and Research, Selaiyur, Chennai, India; 2Dept. of Physiology, Indira Medical College and Hospital, Thiruvallur, Tamilnadu, India;, 3Dept. of Physiology, Tagore Medical College and Hospital, Rathinamangalam, Chennai, India; 4Dept. of General Medicine, Sree Balaji Medical College and Hospital, Chromepet, Chennai, India; *Corresponding Author
Bama Rajanayagam - E-mail: pdcbama@gmail.com
S Manikandan - E-mail: drsmanikandan@gmail.com
NN Anand - E-mail: anandnmd@gmail.com
Article Type
Research Article
Date
Received May 1, 2023; Revised May 31, 2023; Accepted May 31, 2023, Published May 31, 2023
Abstract
Exposure to lethal dust particles has a negative impact on human’s health. This work investigated the association between respiratory symptoms and eosinophil levels between quarry workers and the controls. A total of 75 workers exposed to quarry dust and 45 age, sex, body mass index-matched unexposed controls participated in this study. Results of this study indicated that the quarry dust particles produced inflammatory responses, increasing the mean eosinophil level (7.56 ± 2.94), causing allergic respiratory symptoms such as rhinitis , chest tightness, wheeze, sputum production thus impairing the lung function with decline in FEV1(80.84 ±108.8) level in workers exposed to quarry dust compared to controls (P≤0.00**) Conclusion: The presence of increased levels of respiratory irritants in quarry sites may explain the higher prevalence of respiratory infections and exacerbated inflammatory reactions found to ascertain the link between increased eosinophil count and the lung impairment in quarry workers.
Keywords
Eosinophil count, Deterioration,lung function
Citation
Rajanayagam et al. Bioinformation 19(5): 644-648 (2023)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
