Title

Inflammation in smokers and non-smokers during implant surgery among Indians

Authors

EP Raguladhithya^¹, Sahana Selvaganesh*¹, Thiyaneswaran Nessapan¹, Durairaj Sekar², Vishnu Priya Veeraraghavan² & Rajalakshmanan Eswaramoorthy³

Affiliation

¹Department of Implantology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha university, Chennai 600077, India; ²Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha university, Chennai 600077, India; ³Department of Biomaterials, Centre of Molecular Medicine and Diagnostics (COMManD), Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Medical and Technical Sciences, Saveetha University, Chennai 600077, India. *Corresponding author

Email

EP Raguladhithya – E-mail: raguladhithya496@gmail.comj

Sahana Selvaganesh – E-mail: sahanas.sdc@saveetha.com

Durairaj Sekar E-mail - durairajsekar.sdc@saveetha.com

Thiyaneswaran Nesappan – E-mail: dr.thiyan@gmail.com

Vishnu Priya Veeraraghavan – E-mail: vishnupriya@saveetha.com

Rajalakshmanan Eswaramoorthy – E-mail: rajalakshmanane.sdc@saveetha.com

Article Type

Research Article

Date

Received April 1, 2023; Revised April 30, 2023; Accepted April 30, 2023, Published April 30, 2023

One of the main drawbacks faced by the dental implant surgeons is to assess the healing of the tissues and implant success for patients who are smokers. It is of interest to evaluate inflammatory biomarkers to understand the soft and hard tissue healing between smokers & non-smokers based on levels of IL-6 & STAT-3. This study included totally 20 patients (Group 1 : smokers (n=10) and Group 2: non-smokers (n=10)) undergoing stage-1 implant surgery and collected a tissue sample for the patients to assess the levels of IL-6 & STAT-3. The results indicated that there is a pronounced increase in the biomarkers in patients who are smokers in comparison to non-smokers.

Keywords

Implants, smokers and non-smokers, inflammatory biomarkers, Pro-inflammatory cytokines (IL-6, and STAT-3)

Citation

Raguladhithya et al. Bioinformation 19(4): 510-513 (2023)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.