Title
Data insights from a Moroccan phytochemical database (MPDB) derived from aromatic & medicinal plants
Authors
Lamiae Elkhattabi1,*, Salwa Zouhdi1, Fairouz Mousstead1, Karima Mohtadi1, Hassan Fougrach2, Wadi Badri2, Hassan Taki1, Anass Kettani1, Mohammed Talbi3 & Rachid SAILE1,*
Affiliation
1Laboratory of Biology and Health, Faculty of Sciences Ben M’Sik, Hassan II University of Casablanca, Morocco; 2Laboratory of ecology and environment, Faculty of Sciences Ben M’Sik, Hassan II University of Casablanca, Morocco; 3Laboratoire de Chimie Analytique et Moléculaire LCAM faculté des sciences Ben Msik, Hassan II University of Casablanca, Morocco;
Lamiae Elkhattabi - E-mail: lamiae.elkhattabi-etu@etu.univh2c.ma & lamiaeelkhattabi@gmail.com
Salwa Zouhdi - E-mail: salwa.zouhdi-etu@etu.univh2c.ma
Fairouz Mousstead - E-mail: fairouz.moussetad-etu@etu.univh2c.ma
Karima Mohtadi - E-mail: karima.mohtadi-etu@etu.univh2c.ma
Hassan Fougrach - E-mail: hassan.fougrach@univh2c.ma
Wadi Badri - E-mail: wadi.badri@univh2c.ma
Hassan Taki - E-mail: hassan.taki@univh2c.ma
Anass Kettani - E-mail: anass.kettani@univh2c.ma
Mohammed Talbi - E-mail: talbi.uh2c@gmail.com
Rachid SAILE - E-mail: rachid.saile@univh2c.ma & sailerachid@yahoo.fr
Article Type
Research Article
Date
Received December 1, 2023; Revised December 31, 2023; Accepted December 31, 2023, Published December 31, 2023
Abstract
The geographical location of Morocco and the diversity of its topography ensure a high variability of climate conditions, ranging from humid to Saharan, and extending through subhumid, arid, and semi-arid stages. This variability offers a high floristic diversity, while the medical use of these phytochemicals has not been fully explored. Advanced computer-aided drug discovery utilizes chemical biology to accelerate the study of phytochemicals at the molecular level and discover novel therapeutic pathways. Currently, there is no online resource for phytochemicals in Morocco. Therefore, it is of interest to describe the Moroccan Phytochemicals Database (MPDB), accessible, featuring over 600 phytochemicals derived from journal articles and other reports. The web interface of the database, which is simple and easy to use, provides each phytochemical's reference, plant sources, 3D structures, and all related information. Furthermore, we provide direct links to commercially available analogs from Mcule. In addition, we provide the results of the first virtual screening against cardiovascular targets. We present these data to facilitate further exploration and exploitation of Morocco's rich phytochemical resources, and to contribute to the global understanding and application of these compounds in the medical and scientific communities.
Keywords
aromatic and Moroccan plants, phytochemical database, virtual screening
Citation
Elkhattabi et al. Bioinformation 19(12): 1217-1224 (2023)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
