Title

Biochemical analysis of methanolic extract from Evolvulus alsinoides

Authors

Karnam Nithya¹*, Rajaram Siddaraman², PP Sheelajoice³, Mani Rajarathinam⁴ & Vurimi Bhopal Chandra⁵

Affiliation

¹Department Of Pharmacology, Vinayaka Missions University, Salem, Chinna Seeragapadi, Salem - 636308, Tamilnadu, India; ²Department of Pharmacology, VMKV Medical College, Chinna Seeragapadi, Salem - 636308, Tamil Nadu, India; ³Department Of Physiology, VMKV Medical College, Chinna Seeragapadi, Salem - 636 308, Tamil Nadu, India; ⁴Department Of Pharmacology, GMKMC Medical College, Shavapet Salem 636002, Tamil Nadu, India; ⁵Department of Pharmacology, Narayana Medical College, Nellore - 524 003, AP, India;

Email

Karnam Nithya - E-mail - nithyasree13@gmail.com

Rajaram Siddaraman - E-mail - drrjrm@gmail.com

PP Sheelajoice - E-mail - sheelapaul05@gmail.com

Mani Rajarathinam - E-mail - drmanivp@gmail.com

Vurimi Bhopal Chandra - E-mail - bhopalchandra@gmail.com

Article Type

Research Article

Date

Received December 1, 2023; Revised December 31, 2023; Accepted December 31, 2023, Published December 31, 2023

Evolvulus alsinoides is a medicinal plant in the Convolvulaceae family. Traditionally, it is used for different ailments in India and in several other countries. It has a variety of pharmacological qualities, including those that aid wound healing, hepato-protection, cardio-protection, anti-diabetic action, asthma, and epilepsy, memory and learning, and neuroprotection. The whole plant is utilized in Ayurvedic medicine to treat neurological disorders, including amnesia, and it is called the brain tonic by them. Therefore, the use of GC-MS in phytochemical research and chemotaxonomic investigations of medicinal plants containing physiologically active components is critical. Hence, the various secondary metabolites from the methanolic extract of E. alsinoides were analyzed using GC-MS technique. The methanolic extract of E. alsinoides yielded ten compounds. All ten compounds showed the highest number of hits. Those with the highest concentration were chosen to identify the qualitative compound. All compounds are non-toxic. Molecules with specific properties are capable of modulating a variety of proteins, including some enzymes. Thus, these molecules are potential hit-to-lead molecules in preclinical studies.

Keywords

Phytochemistry, Evolvulus alsinoides, convolvulaceae, GCMS

Citation

Nithya et al. Bioinformation 19(12): 1173-1178 (2023)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.