Title
Up regulated virulence genes in M. tuberculosis H37Rv gleaned from genome wide expression profiles
Authors
Rohini Kumari & Pramod Katara*
Affiliation
Computational Omics Lab, Centre of Bioinformatics, University of Allahabad, Prayagraj, Uttar Pradesh - 211002 India; *Corresponding author
Pramod Katara E-mail: pmkatara@gmail.com & pkatara@allduniv.ac.in
Article Type
Research Article
Date
Received May 13, 2021; Revised May 30, 2021; Accepted May 30, 2021, Published June 30, 2021
Abstract
Identification of up regulated virulence genes in M. tuberculosis H37Rv using genome wide expression profiles is of interest in drug discovery for the disease. Hence, we report 17 up-regulated PPIN (Protein-Protein Interaction Network) enriched potential virulence linked genes using expression data available at the Gene Expression Omnibus (GEO) database for further consideration.
Keywords
Tuberculosis, expression profiling and virulence genes
Citation
Kumari & Katara, Bioinformation 17(6): 608-615 (2021)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
