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Title

Up regulated virulence genes in M. tuberculosis H37Rv gleaned from genome wide expression profiles

 

Authors

Rohini Kumari & Pramod Katara*

 

Affiliation

Computational Omics Lab, Centre of Bioinformatics, University of Allahabad, Prayagraj, Uttar Pradesh - 211002 India; *Corresponding author

 

Email

Pramod Katara E-mail: pmkatara@gmail.com & pkatara@allduniv.ac.in

 

Article Type

Research Article

 

Date

Received May 13, 2021; Revised May 30, 2021; Accepted May 30, 2021, Published June 30, 2021

 

Abstract

Identification of up regulated virulence genes in M. tuberculosis H37Rv using genome wide expression profiles is of interest in drug discovery for the disease. Hence, we report 17 up-regulated PPIN (Protein-Protein Interaction Network) enriched potential virulence linked genes using expression data available at the Gene Expression Omnibus (GEO) database for further consideration.

 

Keywords

Tuberculosis, expression profiling and virulence genes

 

Citation

Kumari & Katara, Bioinformation 17(6): 608-615 (2021)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.