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Title

Molecular docking analysis of potential compounds from an Indian medicinal soup “kabasura kudineer” extract with IL-6

 

Authors

S. Saleem Basha1, Dhirendra Tripathi2, Sravanthi Koora3, K. Satyanarayana4* & Selvaraj Jayaraman5

 

Affiliation

1Department of Medical Biochemistry, School of Medicine, Haramaya University, Harar Campus, Ethiopia; 2Department of Otorhinolaryngology, Government Medical College, Shivpuri, Shivpuri- 473638; 3Department of Pharmacology, Government Medical College Siddipet-502103, Siddipet, Telangana; 4Department of Biochemistry, Government Medical College Siddipet, Siddipet 502103 Telangana India; 5Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai-600 077, India,

 

Email

Dr. K.Satyanarayana - Email ID: satya79700@gmail.com Corresponding author*

 

Article Type

Research Article

 

Date

Received April 25, 2021; Revised May 27, 2021; Accepted May 28, 2021, Published May 31, 2021

 

Abstract

The use of “kabasura kudineer” (liquid soup made from Indian medicinal plants) for combating COVID-19 has been common in the states of Tamilnadu and Puducherry, India during the pandemic. Therefore, it is of interest to document the molecular docking analysis of IL-6 inhibitors with potential antiviral compounds from “kabasura kudineer” extract. We show the optimal binding features of gallic acid and luteolin with the Interleukin-6 protein for further consideration.

 

Keywords

Molecular docking, IL-6, CoVid-19, “kabasura kudineer”

 

Citation

Saleem Basha et al. Bioinformation 17(5): 568-572 (2021)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.