Molecular docking analysis of phytocompounds from Acacia farnesiana with protein targets linked to bronchitis

HOME | PDF |

Title	*Molecular docking analysis of phytocompounds from Acacia farnesiana* with protein targets linked to bronchitis**
Authors	Mallikarjun S Beelagi¹, Manoj Manjunath Bongale², Anisha S Jain⁶, Kollur Shiva Prasad³, Sharanagouda S Patil⁴, Govindappa Mellappa⁵, Chandan Dharmashekar¹, P Ashwini⁶, R Triveni⁷, Chandan Shivamallu¹, ^, Chandrashekar Srinivasa^2,
Affiliation	¹Department of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru, Karnataka 570015, India. ²Department of studies in Biotechnology, Davangere University, Davangere 577007, Karnataka, India; ³Department of Sciences, Amrita School of Arts and Sciences, Amrita Vishwa Vidyapeetham, Mysuru Campus, Mysuru, Karnataka 570 026, India. ⁴ICAR, National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, Bengaluru 560064, India. ⁵Department of Studies in Botany, Davangere University, Davangere 577007, Karnataka, India. ⁶Department of Microbiology, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru, Karnataka–570 015, India; ⁷Sri HN Ananth Kumar, P.U. College, Bidadi 562109, Karnataka, India;
Email	*Correspondence: chandans@jssuni.edu.in (CS); chandru.s@davangereuniversity.ac.in
Article Type	Research Article
Date	Acacia farnesiana, acute bronchitis, molecular docking, discovery studio, phytocompounds
Abstract	Acute bronchitis is a lower respiratory tract lung infection that causes bronchial inflammation. The known protein drug targets are peptidoglycan D, Dtranspeptidase, and DNA topoisomerase 4 subunit A for bronchitis linked infections. These are the membrane associated macromolecules which takes a major role in the formation of cell wall membrane by synthesising the cross-linked peptidoglycan. Therefore, it is of interest to design molecules with improved binding features with these protein targets. Hence, we document the molecular docking analysis data of four phytocompounds from Acacia farnesiana having optimal binding features with these targets linked to bronchitis for further consideration.
Keywords	Acacia farnesiana, acute bronchitis, molecular docking, discovery studio, phytocompounds
Citation	Beelagi et al. Bioinformation 17(5): 557-567 (2021)
Edited by	P Kangueane
ISSN	0973-2063
Publisher	Biomedical Informatics
License	This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.