Title

Differential prolactin levels among male and female patients with thyroid related complains in the Hail regions of Saudi Arabia

Authors

Gamal Mohamed Elawad Ahmed¹, Jerold Casem Alcantara¹, Samir Abdulkarim Alharbi², Waled
Mansi Alshammari³, Fawaz Dabae Alshammari^1,*, Ibtihag Siddig Elnaem⁴, Abdelmuhsin Omer
Ahmed Hassan¹, Khalid Sowilih Alrashedi⁵, Ahmed Abdulaziz Al Tayyar⁵, Turky Ali K. Alreshidi⁵

Affiliation

¹Department of Clinical Laboratory Science, College of Applied Medical Sciences, University of Hail, Saudi Arabia; ²Department of Clinical Laboratory Science, College of Applied Medical Sciences, Shaqra University, Saudi Arabia; ³Hail King Khaled Hospital, Hail, Saudi Arabia; ⁴College of Dentistry, University of Hail, Saudi Arabia; ⁵Hail Regional Laboratory, Hail, Saudi Arabia;

Email

Fawaz Dabae Alshammari – E-mail:fawazaboff@gmail.com; *Corresponding author

Article Type

Research Article

Date

Received September 14, 2019; Revised September 27, 2019; Accepted September 30, 2019; Published October 9, 2019

Thyroid diseases are caused by autoimmunity due to hormone imbalance both in male and female patients. Therefore, it is of acute importance to measure, analyze and compare thyroid hormone levels among populations with thyroid-related complications. Hence, we examined 202 male and female thyroid patients in the Hail regions of Saudi Arabia and estimated their hormone levels. Blood samples were collected from patients and processed for the hormonal profiling such as prolactin, luteinizing hormone (LH), FSH, free T3 (FT3), free T4 (FT4) and TSH3. Further, measurement of thyroid gland size in the Hail population was also completed. Results of our study showed a significant difference in the level of prolactin between male and female patients. Other hormones are namely luteinizing hormone (LH), FSH, free T3 (FT3), free T4 (FT4), TSH3 did not show any significant difference between male and female patients with thyroid disorder.
Thus, the levels of the majority of hormones, namely luteinizing hormone (LH), FSH, free T3 (FT3), free T4 (FT4), and TSH3, except prolactin, did not differ significantly between male and female thyroid patients. Validation of the observation using large scale population size is warranted in future investigations.

Keywords

FSH, hormones, luteinizing hormone, prolactin, T3, T4, thyroid disorders, TSH

Citation

Elawad Ahmed et al. Bioinformation 15(9): 633-639 (2019)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics