Title

Current Bioinformatics resources in combating infectious diseases

Authors

Amr T. M. Saeb^1*

Affiliation

¹Genetics and Biotechnology Department, Strategic Center for Diabetes Research, College of medicine, King Saud University, KSA;

Email

saeb.1@osu.edu

Article Type

Review

Date

Received December 23, 2017; Revised January 16, 2018; Accepted January 17, 2018; Published January 31, 2018

Bioinformatics tools and techniques analyzing next-generation sequencing (NGS) data are increasingly used for the diagnosis and monitoring of infectious diseases. It is of interest to review the application of bioinformatics tools, commonly used databases and NGS data in clinical microbiology, focusing on molecular identification, genotypic, microbiome research, antimicrobial resistance analysis and detection of unknown disease-associated pathogens in clinical specimens. This review documents available bioinformatics resources and databases that are used by medical microbiology scientists and physicians to control emerging infectious pathogens.

Keywords

Next-generation sequencing, pathogen identification, whole genome sequencing, genotyping, ribosomal (rRNA) gene, pathogenicity, virulence and resistome.

Citation

Saeb. Bioinformation 14(1): 031-035 (2018)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.