Title |
Predictive characterization of hypothetical proteins in Staphylococcus aureus NCTC 8325 |
Authors |
Kuana School1, Jessica Marklevitz1, William K. Schram2, Laura K. Harris1* |
Affiliation |
1Department of Science, Davenport University, 200 S. Grand Ave, Lansing, Michigan, 48933, United States of America; 2Department of Science, Davenport University, 27650 Dequindre Rd, Warren, Michigan, 48092, United States of America; |
|
Laura K. Harris - E-mail: laura.harris@davenport.edu; Phone: (517) 719-1729; *Corresponding author |
Article Type |
Hypothesis |
Date |
Received May 16, 2016; Accepted June 6, 2016; Published June 15, 2016 |
Abstract |
Staphylococcus aureus is one of the
most common hospital acquired infections. It colonizes
immunocompromised patients and with the number of antibiotic
resistant strains increasing, medicine needs new treatment options.
Understanding more about the proteins this organism uses would
further this goal. Hypothetical proteins are sequences thought to
encode a functional protein but for which little to no evidence of
that function exists. About half of the genomic proteins in
reference strain S. aureus NCTC 8325 are hypothetical. Since
annotation of these proteins can lead to new therapeutic targets, a
high demand to characterize hypothetical proteins is present. This
work |
Keywords |
S. aureus, characterization, hypothetical proteins |
Citation |
School et al. Bioinformation 12(3): 209-220(2016) |
Edited by |
P Kangueane |
ISSN |
0973-2063 |
Publisher |
|
License |
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License. |