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Title

TmiRUSite and TmiROSite scripts: searching for mRNA fragments with miRNA binding sites with encoded amino acid residues

 

Authors

Olga Berillo1*, Mireille Régnier2 & Anatoly Ivashchenko1

 

Affiliation

1National nanotechnology laboratory, al-Farabi Kazakh National University, Almaty, Kazakhstan; 2INRIA/LIX team AMIB 1 rue Honoré d'Estienne d'Orves 91120 Palaiseau, France

 

Email

devolia18@mail.ru; *Corresponding authors

 

Article Type

Software

 

Date

Received July 03, 2014; Accepted July 11, 2014; Published July 22, 2014

 

Abstract

microRNAs are small RNA molecules that inhibit the translation of target genes. microRNA binding sites are located in the untranslated regions as well as in the coding domains. We describe TmiRUSite and TmiROSite scripts developed using python as tools for the extraction of nucleotide sequences for miRNA binding sites with their encoded amino acid residue sequences. The scripts allow for retrieving a set of additional sequences at left and at right from the binding site. The scripts presents all received data in table formats that are easy to analyse further. The predicted data finds utility in molecular and evolutionary biology studies. They find use in studying miRNA binding sites in animals and plants.

 

Availability

TmiRUSite and TmiROSite scripts are available for free from authors upon request and at https: // sites.google.com/site/malaheenee/downloads for download.

 

Keywords

python script, evolution, mRNA, miRNA.

 

Citation

Berillo et al. Bioinformation 10(7): 472-473 (2014)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.