Title

Authors

Affiliation

¹Department of Pharmacology & Therapeutics, King George’s Medical University, Lucknow-226003, Uttar Pradesh, India; ²Department of Neurology, King George’s Medical University, Lucknow-226003, Uttar Pradesh, India

Email

pharmacsmmu01@gmail.com; *Corresponding authors

Article Type

Hypothesis

Date

Received June 07, 2014; Accepted June 07, 2014; Published June 30, 2014

Parkinson’s disease is the second most common neurodegenerative disorder. The exact cause of selective dopaminergic neurodegeneration is unknown, but it is supposed that etiology of Parkinson’s disease is multifactorial and consists of an interaction between environmental factors and genetic predisposition. To find out the association between environmental factors and risk of Parkinson’s disease, a case control study was designed including 97 Parkinson’s disease patients and 97 controls. Logistic regression analysis was used to determine the risk factors for Parkinson’s disease. Results from the present study showed that gender, religion, education, place of living, occupation, dietary habits, tobacco chewing, smoking, alcohol intake, and head injury had no association with PD. However, chemical exposure and well water drinking were significantly associated with PD, which concluded that environmental factors could act as a risk factor for PD in some way.

Keywords

Parkinson’s disease, risk factors, chemical exposure, well water.

Citation

Gupta et al. Bioinformation 10(6): 342-346 (2014)
 

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.