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DB Dehydrogenase: an online integrated structural database on enzyme dehydrogenase



Suman Kumar Nandy1, Rajabrata Bhuyan1, 2 & Alpana Seal1, 2*



1Department of Biochemistry & Biophysics, University of Kalyani, Kalyani, Dt. - Nadia, West Bengal, India; 2BIF Centre, University of Kalyani, Kalyani, Dt - Nadia, West Bengal, India.


Email; *Corresponding author


Article Type



Received September 26, 2012; Accepted October 04, 2012; Published October 13, 2012



Dehydrogenase enzymes are almost inevitable for metabolic processes. Shortage or malfunctioning of dehydrogenases often leads to several acute diseases like cancers, retinal diseases, diabetes mellitus, Alzheimer, hepatitis B & C etc. With advancement in modern-day research, huge amount of sequential, structural and functional data are generated everyday and widens the gap between structural attributes and its functional understanding. DB Dehydrogenase is an effort to relate the functionalities of dehydrogenase with its structures. It is a completely web-based structural database, covering almost all dehydrogenases [~150 enzyme classes, ~1200 entries from ~160 organisms] whose structures are known. It is created by extracting and integrating various online resources to provide the true and reliable data and implemented by MySQL relational database through user friendly web interfaces using CGI Perl. Flexible search options are there for data extraction and exploration. To summarize, sequence, structure, function of all dehydrogenases in one place along with the necessary option of cross-referencing; this database will be utile for researchers to carry out further work in this field.





Dehydrogenase, Database, Oxidoreductase, Structure, Annotation



Nandy et al. Bioinformation 8(20): 1000-1002 (2012)

Edited by

P Kangueane






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.