Title

Authors

Affiliation

Department of Bioinformatics, School of Biotechnology and Health Sciences, Karunya University, Karunya Nagar, Coimbatore 641114

Email

ersekaran@gmail.edu; *Corresponding author

Article Type

Hypothesis

Date

Received December 27, 2011; Accepted May 11, 2012; Published June 16, 2012

Carbon distribution is responsible for stability and structure of proteins. Arrangement of carbon along the protein sequence is depends on how the amino acids are organized and is guided by mRNAs. An atomic level revision is important for understanding these codes. This will ultimately help in identification of disorders and suggest mutations. For this purpose a carbon distribution analysis program has been developed. This program captures the hydrophobic / hydrophilic / disordered regions in a protein. The program yields thin-skinned results. The calculations are precise and sensitive to single amino acid resolution. This program is hoped to help in mutational studies leading to protein stabilisation.

Keywords

CARd, Carbon distribution, Mutational study, Hydrophobic hydrophilic, Program, Protein disorder, Hydropathy

Citation

Rajasekaran, Bioinformation 8(11): 508-512 (2012)
 

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.