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Title

DDTRP: Database of Drug Targets for Resistant Pathogens

 

Authors

Jagadish Chandrabose Sundaramurthi, Prabhakaran Ramanandan, Sridharan Brindha, Chelladurai Ramarathnam Subhasree, Abhimanyu Prasad, Vasanthapuram Kumaraswamy, Luke Elizabeth Hanna*

 

Affiliation

ICMR-Biomedical Informatics Centre, Tuberculosis Research Centre (ICMR), Chetpet, Chennai-600031, Tamil Nadu, India

 

Email

hannatrc@yahoo.com; *Corresponding author

 

Phone

+91-44-2836 9597

 

Fax

+91-44-2836 2528

 

Article Type

Database

 

Date

Received June 06, 2011; Accepted July 21, 2011; Published September 06, 2011

 

Abstract

Emergence of drug resistance is a major threat to public health. Many pathogens have developed resistance to most of the existing antibiotics, and multidrug-resistant and extensively drug resistant strains are extremely difficult to treat. This has resulted in an urgent need for novel drugs. We describe a database called ‘Database of Drug Targets for Resistant Pathogens’ (DDTRP). The database contains information on drugs with reported resistance, their respective targets, metabolic pathways involving these targets, and a list of potential alternate targets for seven pathogens. The database can be accessed freely at http://bmi.icmr.org.in/DDTRP.

 

Keywords

DDTRP, drug targets, resistant pathogens, database, drug discovery

 

Availability

http://bmi.icmr.org.in/DDTRP

 

Citation

Sundaramurthi et al. Bioinformation 7(2): 98-101 (2011)
 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.