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Title |
DDTRP: Database of Drug Targets for Resistant Pathogens |
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Authors |
Jagadish Chandrabose Sundaramurthi, Prabhakaran Ramanandan, Sridharan Brindha, Chelladurai Ramarathnam Subhasree, Abhimanyu Prasad, Vasanthapuram Kumaraswamy, Luke Elizabeth Hanna* |
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Affiliation |
ICMR-Biomedical Informatics Centre, Tuberculosis Research Centre (ICMR), Chetpet, Chennai-600031, Tamil Nadu, India
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hannatrc@yahoo.com; *Corresponding author
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Phone |
+91-44-2836 9597
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Fax |
+91-44-2836 2528
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Article Type |
Database
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Date |
Received June 06, 2011; Accepted July 21, 2011; Published September 06, 2011
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Abstract |
Emergence of drug resistance is a major threat to public health. Many pathogens have developed resistance to most of the existing antibiotics, and multidrug-resistant and extensively drug resistant strains are extremely difficult to treat. This has resulted in an urgent need for novel drugs. We describe a database called ‘Database of Drug Targets for Resistant Pathogens’ (DDTRP). The database contains information on drugs with reported resistance, their respective targets, metabolic pathways involving these targets, and a list of potential alternate targets for seven pathogens. The database can be accessed freely at http://bmi.icmr.org.in/DDTRP.
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Keywords |
DDTRP, drug targets, resistant pathogens, database, drug discovery
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Availability |
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Citation |
Sundaramurthi et al.
Bioinformation 7(2): 98-101 (2011) |
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Edited by |
P Kangueane
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ISSN |
0973-2063
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Publisher |
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License |
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License. |