Title

Authors

Affiliation

Department of Plant Physiology and Molecular Biology, University of Plovdiv, 24 Tsar Assen St, 4000 Plovdiv, Bulgaria

Email

vebaev@gmail.com; *Corresponding author

Article Type

Web Server

Date

Received April 05, 2011; Accepted April 25, 2011; Published June 06, 2011

MicroRNAs (miRNAs) are important negative regulators of gene expression in plant and animals, which are endogenously produced from their own genes. Computational comparative approach based on evolutionary conservation of mature miRNAs has revealed a number of orthologs of known miRNAs in different plant species. The homology-based plant miRNA discovery, followed by target prediction, comprises several steps, which have been done so far manually. Here, we present the bioinformatics pipeline miRTour which automates all the steps of miRNA similarity search, miRNA precursor selection, target prediction and annotation, each of them performed with the same set of input sequences.

Keywords

microRNAs, microRNAs targets, plant miRNA homologs 

Availability

http://bio2server.bioinfo.uni-plovdiv.bg/miRTour/

Citation

Milev et al. Bioinformation 6(6): 248-249 (2011)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.