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Title |
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CARBANA: Carbon analysis program for protein sequences |
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Authors |
Ekambaram Rajasekaran*, Marimuthu Vijayasarathy |
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Affiliation |
Department of Bioinformatics, School of Biotechnology and Health Sciences, Karunya University, Coimbatore-641114, Tamil Nadu, India |
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ersekaran@gmail.com; *Corresponding author |
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Article Type |
Software
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Date |
Received November 01, 2010; Accepted January 29, 2011; Published February 15, 2011 |
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Abstract |
There are lots of works gone into proteins to understand the nature of proteins. Hydrophobic interaction is the dominant force that drives the proteins to carry out the biochemical reactions in all living system. Carbon is the only element that contributes towards this hydrophobic interaction. Studies find that globular proteins prefer to have 31.45% of carbon for its stability. Taking this as standard, a carbon analysis program has been developed to study the carbon distribution profile of protein sequences. This carbon analysis program has been made available online. This can be accessed at www.rajasekaran.net.in/tools/carbana.html. This new program is hoped to help in identification and development of active sites, study of protein stability, evolutionary understating of proteins, gene identification, ligand binding site identification, and to solve the long-standing problem of protein-protein and protein-DNA interactions. |
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Citation |
Rajasekaran & Vijayasarathy, Bioinformation 5(10): 455-457 (2011) |
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Edited by |
IR Konieczna |
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ISSN |
0973-2063
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Publisher |
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License |
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License. |