BACK TO CONTENTS   |    PDF   |    PREVIOUS   |    NEXT

Title

 

 

 

 

Toward multimodality oral cancer diagnosis in the XXI century: Blending cutting edge imaging and genomic/proteomic definition of suspicious lesions 

Authors

Anh D Le1*, Diana V Messadi2, Joel B Epstein3, Petra Wilder-Smith4

Affiliation

1Center for Craniofacial Molecular Biology, University of Southern California, School of Dentistry, Los Angeles, CA 90033; 2Section of Oral Medicine, Division of Oral Biology & Medicine, UCLA School of Dentistry, University of California, Los Angeles, CA 90095; 3College of Dentistry and Cancer Center, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612; 4Beckman Laser Institute, University of California, Irvine 1002 Health Sciences Rd East, Irvine, CA 92612 

Email

rmanisha@ucla.edu

Article Type

Current Trends

 

Date

Received September 17, 2010; Accepted October 9, 2010; Published January 06, 2011
 

Abstract

If emergent genomic and proteomic approaches to early oral cancer detection are to be successful, a means of reliably and comprehensively identifying high-risk tissue sampling sites constitutes an essential step in the oral cancer screening process. Recent studies have determined that in vivo Optical Coherence Tomography (OCT) is a quick and user-friendly tool for detecting and mapping oral lesions, and that it can enhance diagnostic accuracy when using high resolution diagnostic techniques such as in vivo microscopy. Therefore OCT can potentially provide a means of improving the clinical usefulness of novel diagnostic approaches such as proteomics by identifying sites that need to be sampled  

Citation

Le et al. Bioinformation 5(7): 304-306 (2011)

Edited by

Francesco chiappelli

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.